… a multiscale modelling view of drug discovery, call for a seamless flow of information in the
form of models, and … Therefore, we call for a systematic, multiscale study of drug mechanism, …

… to study and describe the dynamics and mechanisms of drug actions on tumor growth and
… systematic ways of understanding the mechanisms of drug action and adverse responses in …

… New approaches in multiscale modeling and simulation are now being developed to bridge
… drug development and screening, predict drug mechanisms and responses, optimize drug …

… The mechanisms of drug interaction with the heart are very complex and the effects span
from the ion channel to the whole organ level. This makes their investigation using solely …

… In this approach, which focuses on what we term multiscale mechanisms, black-box … with
a broad view of drug action rooted in molecular interactions between the drug and its targets in …

… our understanding of complex mechanisms and our ability to … driving advances in multiscale
modelling methods capable of … -rich, physics-based multiscale approaches are on the cusp …

… A possibility to circumvent the drug toxicity … mechanisms studied with the help of different
experimental approaches, we move on to overview recent developments in theoretical models …

… multiscale frameworks of various types, and selected applications to biomolecular systems
with a focus on drug–… Simulations can reveal molecular mechanisms and analyze them in a …

… Quinidine was discovered more than a century ago as a drug to treat cardiac … multiscale
computational model will become a useful tool to better understand the mechanisms of drug…

… In particular, we suggest that multiscale and multilevel modelling approaches could potentially
provide new insights into AD mechanisms, and towards discovering novel 5-HTR based …