Mutational insights into the envelope protein of SARS-CoV-2

MS Rahman, MN Hoque, MR Islam, I Islam, ID Mishu… - Gene reports, 2021 - Elsevier
… Our study provides a global insight of E gene mutations, and its likely consequences on
primer-based detection of SARS-CoV-2 by RT-PCR method. Overall, this study warrants …

[HTML][HTML] Insights on the mutational landscape of the SARS-CoV-2 Omicron variant

NL Miller, T Clark, R Raman, R Sasisekharan - BioRxiv, 2021 - ncbi.nlm.nih.gov
… We note certain RBD mutations that might further enhance … surveillance of two subclades
bearing R346S/K mutations with … highlight two mechanisms by which these RBD mutations may …

Insights on the mutational landscape of the SARS-CoV-2 Omicron variant receptor-binding domain

NL Miller, T Clark, R Raman, R Sasisekharan - Cell Reports Medicine, 2022 - cell.com
… Using AAI, we map Omicron mutations directly and indirectly driving increased escape …
sequence or point mutation analyses. Finally, for several Omicron RBD mutations, we find …

[PDF][PDF] Insilico insights to mutational and evolutionary aspects of sars-COV2

S Menon - World Health, 2020 - academia.edu
… the possible role of these mutations in viral structural proteins. Our detailed examination
of many SARS-CoV-2 structural protein mutations revealed that L37H mutation in E protein, …

[HTML][HTML] Insights on early mutational events in SARS-CoV-2 virus reveal founder effects across geographical regions

C Farkas, F Fuentes-Villalobos, JL Garrido, J Haigh… - PeerJ, 2020 - peerj.com
… describe early mutational events across samples from publicly available SARS-CoV-2
sequences … A total of 30 datasets (60%) contain at least a single founder mutation and most of the …

… genome analysis of novel coronavirus (SARS-CoV-2) from different geographical locations and the effect of mutations on major target proteins: An in silico insight

MI Khan, ZA Khan, MH Baig, I Ahmad, AEA Farouk… - PLoS …, 2020 - journals.plos.org
… entry of virus particle. This study provides a deeper insight into the emergence of these
mutations within the major structural as well as nsp encoded by the SARS-CoV-2 genome from …

Genetic analysis of SARS-CoV-2 isolates collected from Bangladesh: Insights into the origin, mutational spectrum and possible pathomechanism

MSA Parvez, MM Rahman, MN Morshed… - … biology and chemistry, 2021 - Elsevier
… preliminary insights into the origin of Bangladeshi SARS-CoV-2 isolates, mutation spectrum
… an essential clue for designing therapeutics and management of COVID-19 in Bangladesh. …

… evolutionary plasticity of coronaviruses by mutation and recombination: insights for the COVID-19 pandemic and the future evolutionary paths of SARS-CoV-2

GD Amoutzias, M Nikolaidis, E Tryfonopoulou… - Viruses, 2022 - mdpi.com
… over the last two years that reveal the impact of point mutations, … of CoV vaccines should be
directed against other CoV … evolutionary path of SARS-CoV-2 and the COVID-19 pandemic. …

Insights into SARS-CoV-2's mutations for evading human antibodies: sacrifice and survival

B Luan, T Huynh - Journal of medicinal chemistry, 2021 - ACS Publications
insights into why K417N has been selected during viral evolution and inspire a better
design of more efficacious mAbs for treating COVID-19 patients infected with the new SARS-CoV-2

Emergence of genomic diversity and recurrent mutations in SARS-CoV-2

L Van Dorp, M Acman, D Richard, LP Shaw… - Infection, Genetics and …, 2020 - Elsevier
insights into the past demography of SARS-CoV-2 but also … By focusing on mutations which
have emerged independently … 198 filtered recurrent mutations in the SARS-CoV-2 genome. …