J Wang, L Chen, P Qiang - OncoTargets and therapy, 2020 - Taylor & Francis
N6-methyladenosine (m6A) demethylase fatmass and obesity-associated gene(FTO), previously recognized to be related with obesity and diabetes, was gradually discovered to be …
T Pan - Trends in biochemical sciences, 2013 - cell.com
… of a mammalian enzyme that removes m 6 A and the application of deep sequencing to localize modification sites. The m 6 A demethylase fatmass and obesity associated protein (FTO…
… We and others have previously reported that experimental stroke in rodents triggers m 6 A hypermethylation and a concomitant downregulation of m 6 A demethylase FTO (fatmass and …
J Chen, X Zhou, W Wu, X Wang, Y Wang - Journal of physiology and …, 2015 - Springer
… status of m 6 A mRNA methylation and expression of the fatmass and obesity-associated gene (FTO), which exerted an oxidative demethylation activity targeting m 6 A residues in RNA. …
HJ Shan, WX Gu, G Duan, HL Chen - Bioengineered, 2022 - Taylor & Francis
N6-methyladenosine (m6A) methylation is the most common and abundant methylation modification of eukaryotic mRNAs, which is involved in tumor initiation and progression. The …
A Strick, F von Hagen, L Gundert, N Klümper… - BJU …, 2020 - Wiley Online Library
Objectives To comprehensively investigate the role of the N 6 ‐methyladenosine (m 6 A) erasers ALKBH5 and FTO in clear cell renal cell carcinoma (ccRCC), other RCC subtypes, and …
Y Wu, J Li, C Li, S Lu, X Wei, Y Li, W Xia, C Qian… - Journal of Biological …, 2023 - ASBMB
N6-methyladenosine (m6A) is the most prevalent reversible RNA modification in the mammalian transcriptome. It has recently been demonstrated that m6A is crucial for male germline …
X Zhou, J Chen, J Chen, W Wu, X Wang… - The Journal of Nutritional …, 2015 - Elsevier
… These changes were also accompanied with decreased epididymal fatmass and improved systemic insulin resistance, which was manifested by remarkably decreased circulating FFA …
C Cheng, F Yu, G Yuan, J Jia - Obesity, 2024 - Wiley Online Library
… The regulatory mechanism of N6-methyladenosine (m6A) methylation. The writers are … The m6A demethylation process is mainly mediated by erasers including fatmass- and obesity-…