Biological nanopore approach for single‐molecule protein sequencing

ZL Hu, MZ Huo, YL Ying, YT Long - Angewandte Chemie, 2021 - Wiley Online Library
… to sequentially identify each amino acid (AA) of single proteins due to the inherent … in
biological nanopores for single-molecule protein sequencing (SMPS) from native protein unfolding, …

Engineering biological nanopore approaches toward protein sequencing

X Wei, T Penkauskas, JE Reiner, C Kennard… - ACS …, 2023 - ACS Publications
… the nanopore field from third-generation gene sequencing toward single-molecule proteomics
and perhaps a future of multiomics. Here, we review nanopore protein sequencing from …

Nanopore‐based protein sequencing using biopores: Current achievements and open challenges

A Asandei, G Di Muccio, I Schiopu, L Mereuta… - Small …, 2020 - Wiley Online Library
… and protein … of the nanopore-based investigations of matter at the molecular level. This
review focuses on the fundamental principles of α-hemolysin (α-HL) protein-based nanopores, as …

Protein sequencing via nanopore based devices: a nanofluidics perspective

M Chinappi, F Cecconi - Journal of Physics: Condensed Matter, 2018 - iopscience.iop.org
… of nanopore based devices for protein sequencing. We start with a critical analysis of the
main technical requirements for nanopore protein sequencing, … occurring in nanopore based …

The promise of nanopore technology: Advances in the discrimination of protein sequences and chemical modifications

B Cressiot, L Bacri, J Pelta - Small Methods, 2020 - Wiley Online Library
… the analytical aspect of nanopore recoding, we recommend … sequence analysis, we give
an example with one protein … with other nanopore types, including solid state nanopores, [ …

[HTML][HTML] Nanopore-based technologies beyond DNA sequencing

YL Ying, ZL Hu, S Zhang, Y Qing, A Fragasso… - Nature …, 2022 - nature.com
… of nanopores in molecular sensing and sequencing, … of applying nanopores for single-protein
analysis and sequencing, … nanopore proteomics would be de novo protein sequencing, …

Paving the way to single-molecule protein sequencing

L Restrepo-Pérez, C Joo, C Dekker - Nature nanotechnology, 2018 - nature.com
… A major roadblock for the development of a protein sequencer with nanopores is the non-uniform
charge distribution of amino acid residues. Unlike DNA that is uniformly charged and …

Is the volume exclusion model practicable for nanopore protein sequencing?

MZ Huo, MY Li, YL Ying, YT Long - Analytical Chemistry, 2021 - ACS Publications
… factors such as enhanced nanopore–peptide interactions could … development of nanopore
protein sequencing methods. … further development of nanopore protein sequencing methods. …

[HTML][HTML] Nanopore technology for the application of protein detection

X Zeng, Y Xiang, Q Liu, L Wang, Q Ma, W Ma, D Zeng… - Nanomaterials, 2021 - mdpi.com
… of novel nanopore single-molecule detection technology, its application to protein sequence
… In this paper, the application of nanopore single-molecule detection technology in protein

[HTML][HTML] Insights into protein sequencing with an α-Hemolysin nanopore by atomistic simulations

G Di Muccio, AE Rossini, D Di Marino, G Zollo… - Scientific reports, 2019 - nature.com
… the changes in the nanopore electric resistance induced by … nanopore sensors is the single
molecule protein sequencing. Compared to DNA sequencing, nanopore protein sequencing