Nanopore sequencing of infectious fluid is a promising supplement for gold-standard culture in real-world clinical scenario

M Zhao, Y Zhang, L Chen, X Yan, T Xu, M Fu… - Frontiers in Cellular …, 2024 - frontiersin.org
… This study included seven types of clinical fluids, from 10 clinical centers, and provided …
of nanopore sequencing in real-world clinical scenarios. Nanopore sequencing exhibits fast …

Nanopore sequencing in blood diseases: a wide range of opportunities

CF Minervini, C Cumbo, P Orsini, L Anelli… - Frontiers in …, 2020 - frontiersin.org
Nanopore Technologies (ONT) released the MinION, the first long-read nanopore-based
sequencer… In the last years, several nanopore sequencing approaches have been performed in …

Comparison of illumina and Oxford nanopore sequencing technologies for pathogen detection from clinical matrices using molecular inversion probes

CP Stefan, AT Hall, AS Graham, TD Minogue - The Journal of Molecular …, 2022 - Elsevier
… We describe the ability of Illumina and Oxford Nanopore Technologies (ONT) to sequence
sequencing platforms detected 18 viral and parasitic organisms directly from mock clinical

A multicenter study on accuracy and reproducibility of nanopore sequencing-based genotyping of bacterial pathogens

J Dabernig-Heinz, M Lohde, M Hölzer… - Journal of Clinical …, 2024 - journals.asm.org
… Our study highlights the potential for new errors to appear with each newly sequenced strain
… for a new validation concept for nanopore sequencing-based, standardized bacterial typing, …

[HTML][HTML] Nanopore sequencing technology for clinical diagnosis of infectious diseases where laboratory capacity is meager: A case report

HH Kumburu, M Shayo, M van Zwetslaar, J Njau… - Heliyon, 2023 - cell.com
… However, this kind of scenario is just one among many that are happening in most of our …
hospitals within the country, where nanopore sequencing technology has been deployed on…

An introduction to nanopore sequencing: past, present, and future considerations

M MacKenzie, C Argyropoulos - Micromachines, 2023 - mdpi.com
… to nanopore sequencing principles, discussing biological and solid-state nanopore
We present examples of important clinical applications to give perspective on the potential …

Nanopore sequencing data analysis: state of the art, applications and challenges

A Magi, R Semeraro, A Mingrino, B Giusti… - Briefings in …, 2018 - academic.oup.com
… The nanopore sequencing … Oxford Nanopore Technologies (ONT) launched a beta-testing
program that supplied the scientific community with the first prototype of a nanopore sequencer

[HTML][HTML] Nanopore sequencing technology, bioinformatics and applications

Y Wang, Y Zhao, A Bollas, Y Wang, KF Au - Nature biotechnology, 2021 - nature.com
… to the technology development of nanopore sequencing and discuss improvements in the
… We then review the major applications of nanopore sequencing in basic research, clinical

[HTML][HTML] Performance of metagenomic Next-Generation Sequencing and metagenomic Nanopore Sequencing for the Diagnosis of Tuberculosis in HIV-positive …

J Yuan, L Wang, W Zhang, C Deng, Q Li… - Frontiers in Cellular …, 2024 - frontiersin.org
… performance of mNGS (metagenomic Next-Generation Sequencing) and mNPS (metagenomic
NanoPore Sequencing) for the rapid diagnosis of tuberculosis in HIV-infected patients. …

Assessing the utility of long-read nanopore sequencing for rapid and efficient characterization of mobile element insertions

CM Watson, LA Crinnion, H Lindsay, R Mitchell… - Laboratory …, 2021 - nature.com
sequencing. To validate the accuracy of the long-read technology, we first used Sanger
sequencing … Long-read nanopore sequencing was then performed on locus-specific amplicons. …