Third-generation sequencing in the clinical laboratory: exploring the advantages and challenges of nanopore sequencing

LM Petersen, IW Martin, WE Moschetti… - Journal of clinical …, 2019 - Am Soc Microbiol
… of nanopore sequencing from Oxford Nanopore Technologies (ONT) has the potential to
address these challenges. ONT sequencing … to be developed for each sample type, sequencing

Nanopore sequencing technology and its applications

P Zheng, C Zhou, Y Ding, B Liu, L Lu, F Zhu… - MedComm, 2023 - Wiley Online Library
… In early experiments in the development of nanopore sequencing, single-stranded DNA …
results reveal SARS-CoV-2 evolutionary trends in central India, with the highly infectious spike …

[HTML][HTML] Advances and trends in omics technology development

X Dai, L Shen - Frontiers in Medicine, 2022 - frontiersin.org
… Long-read sequencing technologies such as PacBio and Oxford nanopore sequencing
techniques have thus been adapted for epigenome interrogation. PacBio SMRT, which monitors …

Nanopore sequencing in a clinical routine laboratory: challenges and opportunities.

J Schmidt, F Blessing, L Fimpler… - Clinical …, 2020 - search.ebscohost.com
… Nevertheless, there is considerable active development occurring to increase accuracy and
performance in general. If this trend continues, one can assume that nanopore sequencing

DNA sequencing: an overview of solid-state and biological nanopore-based methods

MM Mohammadi, O Bavi - Biophysical reviews, 2022 - Springer
… Among these generations, nanopore sequencing has its own … Nanopore sequencing
might be the most favorable platform for the development of third-generation DNA sequencing

Nanopore sequencing in blood diseases: a wide range of opportunities

CF Minervini, C Cumbo, P Orsini, L Anelli… - Frontiers in …, 2020 - frontiersin.org
… By combining the MinION system and Anchored Multiplex PCR (AMP)-based libraries, a
nanopore-based sequencing assay was developed to rapidly detect fusion genes in acute …

Nanopore sequencing technology and tools for genome assembly: computational analysis of the current state, bottlenecks and future directions

D Senol Cali, JS Kim, S Ghose, C Alkan… - Briefings in …, 2019 - academic.oup.com
develop better tools. To this end, we (1) analyze the multiple steps and the associated tools
in the genome assembly pipeline using nanopore sequence … and coverage trends among all …

[HTML][HTML] Nanopore sequencing and its application to the study of microbial communities

L Ciuffreda, H Rodríguez-Pérez, C Flores - Computational and structural …, 2021 - Elsevier
… , nanopore sequencing has enhanced our ability to study complex microbial samples through
the possibility to sequence … has developed two 16S barcoding kits for rapid sequencing of …

Nanopore sequencing and its clinical applications

X Sun, L Song, W Yang, L Zhang, M Liu, X Li, G Tian… - Precision Medicine, 2020 - Springer
… The development of long-read sequencing technology has the potential to increase the
detection rate of viral integrations in repeat regions. We introduce two target-enrichment methods …

The potential and challenges of nanopore sequencing

D Branton, DW Deamer, A Marziali, H Bayley… - Nature …, 2008 - nature.com
… with sequencing by synthesis 15,16 , is continued research toward nanopore sequencing
of and the challenges for the development of nanopore sequencing, with a goal of engaging …