Nasal vaccination against SARS-CoV-2: Synergistic or alternative to intramuscular vaccines?

M Tiboni, L Casettari, L Illum - International journal of pharmaceutics, 2021 - Elsevier
… years dealt with nasal versus injectable vaccines in general … vaccination as an alternative
to IM administration of vaccines … existing SARS-CoV-2 vaccines either already marketed or in …

Nasal route for vaccine and drug delivery: Features and current opportunities

YL Mato - International journal of pharmaceutics, 2019 - Elsevier
vaccine delivery. Compelling evidences support the potentialities and safety of the nasal
delivery of vaccines … The majority of available vaccines employ intramuscular or subcutaneous …

Chitosan as a novel nasal delivery system for vaccines

L Illum, I Jabbal-Gill, M Hinchcliffe, AN Fisher… - Advanced drug delivery …, 2001 - Elsevier
… showed that the nasal chitosan influenza vaccine was both … The mechanism of action of the
chitosan nasal vaccine … a single dose of intramuscularly administered trivalent vaccine (3×15 …

Effective nasal influenza vaccine delivery using chitosan

RC Read, SC Naylor, CW Potter, J Bond, I Jabbal-Gill… - Vaccine, 2005 - Elsevier
… statistically different from those for saline vaccines given intramuscularly. This accords with
similar … studies using vaccines formulated with chitosan, strongly support the capacity of such …

Mucosal immunity and nasal influenza vaccination

MA Rose, S Zielen, U Baumann - Expert review of vaccines, 2012 - Taylor & Francis
Nasal influenza immunization has distinct features compared with intramuscular vaccines, …
the experience from clinical trials on the impact and safety of nasal influenza vaccination. …

Nanoparticles for nasal vaccination

N Csaba, M Garcia-Fuentes, MJ Alonso - Advanced drug delivery reviews, 2009 - Elsevier
… Moreover, mucosal vaccines have higher patient compliance than parenteral ones. The
combination of all this factors will most probably imply better patient adhesion to a fixed …

Development of nasal vaccines and the associated challenges

X Nian, J Zhang, S Huang, K Duan, X Li, X Yang - Pharmaceutics, 2022 - mdpi.com
nasal vaccine, split nasal vaccine, subunit nasal vaccine, peptide nasal vaccine, and nucleic
acid nasal vaccine, … route to the currently used intramuscular SARS-CoV-2 vaccine [164]. …

[HTML][HTML] Nasal DNA-MVA SIV vaccination provides more significant protection from progression to AIDS than a similar intramuscular vaccination

M Manrique, PA Kozlowski, SW Wang, RL Wilson… - Mucosal …, 2009 - Elsevier
… , 8 , 9 These vaccines administered intramuscularly (IM) provided a substantially smaller …
to be critical to the protection provided by other vaccines for viral infections. A HIV-expressing …

Nasal delivery of vaccines

AJ Almeida, HO Alpar - Journal of drug targeting, 1996 - Taylor & Francis
… This review describes the formulation of vaccines to be delivered … In this review, the
delivery of nasal vaccines is considered. … Nasal vaccination has been investigated by administering …

Local and systemic immune response in nursing-home elderly following intranasal or intramuscular immunization with inactivated influenza vaccine

M Muszkat, E Greenbaum, A Ben-Yehuda, M Oster… - Vaccine, 2003 - Elsevier
… of nasal vaccines in the elderly compared to parenteral vaccines is not yet clear, nasal
vaccination … The main outcome of this study is that following nasal vaccination mucosal antibody …