J Huang, Y Ding, J Yao, M Zhang, Y Zhang, Z Xie… - Vaccines, 2022 - mdpi.com
… ideal SARS-CoV-2 vaccines can stimulate the nasal mucosa to produce systemic immunity and mucosal immunity. Among them, the nasal … and envelope protein of SARS-CoV-2 can be …
… In this review, we provide an overview of nasalvaccines with a focus on formulation development as well as ongoing preclinical and clinical studies for SARS-CoV-2 intranasal vaccine …
… vaccine demonstrated detectable viral RNA in the nasal swabs of several participants after SARS-CoV… The findings of elevated nasal viral titers despite the effective prevention of COVID-…
N Tokunoh, S Tamiya, M Watanabe… - Frontiers in …, 2023 - frontiersin.org
… Therefore, in this study, we focused on using the inactivated WV as a nasalvaccine against SARS-CoV-2. We examined the potential of an inactivated WV as an antigen to induce S-…
F Liew, S Talwar, A Cross, BJ Willett, S Scott… - …, 2023 - thelancet.com
… We studied nasal and plasma antibody responses one year … a period when SARS-CoV-2 vaccination was introduced. … in nasal and plasma IgA and IgG anti-S titres for all SARS-CoV-2 …
… In this article, the current approaches used to develop effective oral and nasal mucosal vaccines against SARS-CoV-2 and their benefits, prospects, and challenges have been …
R Zhou, P Wang, YC Wong, H Xu, SY Lau, L Liu… - …, 2022 - thelancet.com
… that an effective vaccine should induce mucosal immunity for nasal protection to prevent SARS-CoV-2 asymptomatic infection and silent spread. Recently, thousands of vaccine-…
… vaccination to SARS-CoV, virus-specific Trm cells develop in the lungs, while if the … accumulation of SARS-CoV-2 specific T cells in the UA thanks to a nasalvaccination may guarantee …
J Yeung, T Wang, PY Shi - Current Opinion in Virology, 2023 - Elsevier
… nasalvaccines could further reduce SARS-CoV-2 transmission. We discuss the benefits of intranasal live-attenuated SARS-CoV-2 vaccines, … developing an attenuated vaccine platform. …