Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease

ECB Johnson, S Bian, RU Haque, EK Carter… - Nature medicine, 2023 - nature.com
… Here we show that proteomic measurements in autosomal dominant AD cerebrospinal fluid
(… The proteome discriminated mutation carriers from noncarriers before symptom onset as …

Approaching clinical proteomics: current state and future fields of application in fluid proteomics

R Apweiler, C Aslanidis, T Deufel… - Clinical chemistry and …, 2009 - degruyter.com
… for body fluid proteomics, like any other clinical laboratory … on fluid proteomics and suggest
procedures for sample preparation and standardization of protocols for analysis of body fluids

The human plasma proteome: history, character, and diagnostic prospects

NL Anderson, NG Anderson - Molecular & cellular proteomics, 2002 - ASBMB
… We are currently in the phase of seeking shortcuts through proteomicsproteome. Hence
we have attempted to survey the larger context of the plasma proteome as well as the history

After the Genome—A Brief History of Proteomics

M Suran - JAMA, 2022 - jamanetwork.com
… That human proteome is composed of subproteomes because each cell type has its own
unique proteome. Then there are proteoforms, which make up a proteome, and these …

On the development of proteomics: a brief history

RA Bradshaw - Australian Journal of Chemistry, 2023 - CSIRO Publishing
proteomics as a field as that would require an exact definition of what constitutes a proteomic
… We do know when the term ‘proteome’ was coined by Marc Wilkins in a presentation in Italy …

Biomarker discovery and clinical proteomics

J Silberring, P Ciborowski - TrAC Trends in Analytical Chemistry, 2010 - Elsevier
… New clinical and translational proteomics studies emerge almost every day. … in proteomics
studies (eg, assembly of a cohort of patients, sample preparation and the nature of body fluids, …

Quantitative proteomics and metabolomics analysis of normal human cerebrospinal fluid samples

MP Stoop, L Coulier, T Rosenling, S Shi… - … & Cellular Proteomics, 2010 - ASBMB
… By discovering the characterization of the proteome and metabolome of CSF we may gain
better insight on the pathogenesis of CNS disorders. This would be significant because, for …

Revisiting biomarker discovery by plasma proteomics

PE Geyer, LM Holdt, D Teupser… - Molecular systems biology, 2017 - embopress.org
… (MS)‐based proteomics has become a powerful technology … the characterization of the
plasma proteome in great depth. … ” plasma proteome profiling strategy, in which the proteome

Biomarkers: mining the biofluid proteome

TD Veenstra, TP Conrads, BL Hood, AM Avellino… - … & Cellular Proteomics, 2005 - ASBMB
… in proteomic analyses of biofluids provides plenty of optimism. In particular, proteomics has
… increased our knowledge of the protein content of serum, plasma, and cerebrospinal fluid. …

Proteomics of rat biological fluids—the tenth anniversary update

E Gianazza, R Wait, I Eberini, C Sensi, L Sironi… - … of proteomics, 2012 - Elsevier
… In order to compress in a few weeks/months the natural history of decade-long diseases
all the current models are of necessity are extreme either in the engineering of the genetic …