Crystal structure of NDM1 reveals a common βlactam hydrolysis mechanism

M Zhang, Q Hao - The FASEB Journal, 2011 - Wiley Online Library
… ‐βlactamases (MBLs) hydrolyze most βlactam … (NDM1) is a new member of this family
that shows tight binding to penicillin and cephalosporins. The rapid dissemination of NDM1 in …

Ten years with New Delhi metallo-β-lactamase-1 (NDM-1): from structural insights to inhibitor design

P Linciano, L Cendron, E Gianquinto… - ACS infectious …, 2018 - ACS Publications
NDM-1 are available in therapy, nor are promising compounds in the pipeline for future
NDM-1 … We report the studies dedicated to the design and development of effective NDM-1

New Delhi metallo-β-lactamase (NDM-1): An updates

S Shakil, EI Azhar, S Tabrez, MA Kamal… - Journal of …, 2011 - Taylor & Francis
… dissemination of nDM1 across the globe 22. Recently, Kus et al published the first report
of blanDM-1-positive bacteria which were locally acquired in Canada 23. nDM-1-producing …

Structure of New Delhi metallo-β-lactamase 1 (NDM-1)

VL Green, A Verma, RJ Owens… - … Section F: Structural …, 2011 - journals.iucr.org
… of New Delhi MBL 1 (NDM-1) from Klebsiella pneumoniae, a novel class B1 MBL of great
clinical significance owing to its capacity to hydrolyse a wide range of -lactam antibiotics. …

Increasing prevalence and dissemination of NDM-1 metallo-β-lactamase in India: data from the SMART study (2009)

C Lascols, M Hackel, SH Marshall… - Journal of …, 2011 - academic.oup.com
… bla NDM-1 genes. Primers used have been described previously except those for … NDM-1
, which were designed in this study: NDM-1f 5′-CCGTATGAGTGATTGCGGCG-3′ and NDM-…

New metallo β-lactamase NDM-1

D Raghunath - Indian Journal of Medical Research, 2010 - journals.lww.com
… In summary, NDM1 confers on its host bacteria almost all β lactam resistance and is … isolates
respectively showed 1 and 13 per cent prevalence of NDM1 carrying Enterobacteriaceae. …

Mechanistic and spectroscopic studies of metallo-β-lactamase NDM-1

H Yang, M Aitha, AM Hetrick, TK Richmond… - Biochemistry, 2012 - ACS Publications
In an effort to biochemically characterize metallo-β-lactamase NDM-1, we cloned,
overexpressed, purified, and characterized several maltose binding protein (MBP)–NDM-1 fusion …

How to detect NDM-1 producers

P Nordmann, L Poirel, A Carrër… - Journal of clinical …, 2011 - Am Soc Microbiol
NDM-1 is a broad-spectrum β-lactamase (carbapenemase) that is able to inactivate all β-lactams
except aztreonam (18). However, most NDM-1-positive strains also express the CMY-4 …

New Delhi metallo-beta-lactamase (NDM-1): towards a new pandemia?

JM Rolain, P Parola… - Clinical …, 2010 - clinicalmicrobiologyandinfection …
NDM-1 was first reported in 2009 in a Swedish patient of Indian origin, who travelled to New
NDM-1 positive E. coli as well [6]. The NDM-1 encoding gene is located on different large …

Emergence of NDM-1 Metallo-β-Lactamase in Pseudomonas aeruginosa Clinical Isolates from Serbia

B Jovcic, Z Lepsanovic, V Suljagic… - Antimicrobial agents …, 2011 - Am Soc Microbiol
… -β-lactamase 1 (NDM-1) in Pseudomonas aeruginosa. Moreover, this is the first report of
the NDM-1 … of metallo-β-lactamases. Accordingly, both MMA83 and MMA533 carried the bla …