… NDM-1 are available in therapy, nor are promising compounds in the pipeline for future
NDM-1 … We report the studies dedicated to the design and development of effective NDM-1 …

… NDM-1 was first reported in 2009 in a Swedish patient of Indian origin, who travelled to New
… NDM-1 positive E. coli as well [6]. The NDM-1 encoding gene is located on different large …

… In an effort to biochemically characterize metallo-β-lactamase NDM-1, we cloned, … )–NDM-1
fusion proteins with different N-termini (full-length, Δ6, Δ21, and Δ36). All MBP–NDM-1 fusion …

… Consequently, an infection caused by bacteria possessing the gene for the NDM-1 enzyme
is … of an NDM-1 inhibitor. This review aims to summarize various NDM-1 inhibitor designs that …

… metallo-β-lactamase (MBL) enzymes are responsible for much of this resistance. The recently
identified New Delhi MBL 1 (NDM-1) is … Here, the crystal structure of NDM-1 from Klebsiella …

… metallo-β-lactamase NDM-1, heterodimetallic analogues (CoCo-, ZnCo-, and CoCd-) of
the enzyme were generated and characterized. UV–vis, 1 … preparation of a metallo-β-lactamase …

… is the New Delhi metallo-β-lactamase 1 (NDM-1) that has … NDM-1 encoded by the bla NDM-1
gene was initially identified in a Klebsiella pneumoniae isolate in 2008. Since then, NDM-1 …

… The NDM-1 has an unique additional sequence. The … In summary, NDM1 confers on its host
bacteria almost all β … respectively showed 1 and 13 per cent prevalence of NDM1 carrying …

… simulations of the dizinc metallo form indicates that the … of NDM-1 is similar in structure to
other class B1 metallo-β-lactamases. Supplementation of excess zinc ions to monozinc NDM-1 …

… Here we report hydrolytic activity of NDM-1 against selected β-lactams and carbapenems, …
form of NDM-1 derived from K. pneumoniae. Our results show that NDM-1 is unique among …