Network dynamics in the tumor microenvironment

H Bolouri - Seminars in cancer biology, 2015 - Elsevier
… advantages, resist interventions, and allow tumors to remain dormant for long periods. …
tumor microenvironment. I argue that data-driven molecularly detailed tumor microenvironment

[HTML][HTML] An overview of the tumor microenvironment, from cells to complex networks

O Farc, V Cristea - Experimental and therapeutic …, 2021 - spandidos-publications.com
… Apart from the progress in the molecular and cellular biology, the knowledge of the tumor
microenvironment as a whole, with its complex network of cells and cytokines, will contribute to …

Multiscale network analysis reveals molecular mechanisms and key regulators of the tumor microenvironment in gastric cancer

WM Song, X Lin, X Liao, D Hu, J Lin… - … Journal of Cancer, 2020 - Wiley Online Library
… shown in Figure 1 c and comprehensively investigate their network structures and biological
implications as well as their interactions in the context of GC tumor microenvironment. …

[HTML][HTML] Mining the tissue-tissue gene co-expression network for tumor microenvironment study and biomarker prediction

Y Xiang, J Zhang, K Huang - BMC genomics, 2013 - Springer
… the tumor microenvironment (TME) interacts with the tumor, we explore the correlation of the
gene expressions between tumor … bipartite networks which show orchestrated key biological

[HTML][HTML] Tumor microenvironment—A short review of cellular and interaction diversity

A Bożyk, K Wojas-Krawczyk, P Krawczyk, J Milanowski - Biology, 2022 - mdpi.com
… The tumor microenvironment is a complex network of various interactions between
immune cells and non-cellular components such as the extracellular matrix, exosomes and …

A complex network of tumor microenvironment in human high-grade serous ovarian cancer

C Kreuzinger, A Geroldinger, D Smeets, EI Braicu… - Clinical Cancer …, 2017 - AACR
… at studying the molecular biology of both … microenvironment network including immune
activation and remodeling of tissues around tumors across all tumor samples and defined tumors

[PDF][PDF] Network biology and the 3-Dimensional tumor microenvironment: personalizing medicine for the future

TR Cox, JT Erler - Tumor Microenvironment and Therapy, 2012 - researchgate.net
… Concomitantly, the extrinsic contribution of the tumor microenvironment is now considered …
to network-based, systems biology approaches, and signals the start of the network medicine …

[HTML][HTML] Spatial domain analysis predicts risk of colorectal cancer recurrence and infers associated tumor microenvironment networks

S Uttam, AM Stern, CJ Sevinsky, S Furman… - Nature …, 2020 - nature.com
… Additionally, SpAn infers the emergent network biology of tumor microenvironment spatial
domains revealing a spatially-mediated role of CRC consensus molecular subtype features …

Cancer systems biology: a network modeling perspective

PK Kreeger, DA Lauffenburger - Carcinogenesis, 2010 - academic.oup.com
… Computational models are beginning to provide tools to address how the tumor
microenvironment and growth factor signaling regulate these events. Although numerous models for …

The tumor microenvironment at a glance

FR Balkwill, M Capasso… - Journal of cell …, 2012 - journals.biologists.com
… Intercellular communication is driven by a complex and dynamic network of cytokines,
chemokines, growth factors, and inflammatory and matrix remodeling enzymes against a …