Ageing, cellular senescence and neurodegenerative disease

M Kritsilis, S V. Rizou, PN Koutsoudaki… - International journal of …, 2018 - mdpi.com
cellular senescence as a therapeutic target. Here, we review evidence of cellular senescence
… its putative role in Alzheimer’s disease, Parkinson’s disease and multiple sclerosis and we …

Cellular senescence in neurodegenerative diseases

C Martínez-Cué, N Rueda - Frontiers in cellular neuroscience, 2020 - frontiersin.org
… of cellular senescence in the neurodegenerative diseases … role of cellular senescence in the
neurodegenerative diseases AD… three diseases, they are characterized by senescence and …

[HTML][HTML] Evidence and perspectives of cell senescence in neurodegenerative diseases

Z Si, L Sun, X Wang - Biomedicine & Pharmacotherapy, 2021 - Elsevier
senescent cells in neurodegenerative diseases. In the final section, we review how cell
senescence … novel therapeutics to treat pathologies associated with neurodegenerative diseases. …

Molecular mechanisms of cellular senescence in neurodegenerative diseases

HJ Lee, YS Yoon, SJ Lee - Journal of molecular biology, 2023 - Elsevier
… certain molecules via senescence-associated secretory phenotype (SASP). In this review, we
… how cellular senescence contributes to brain aging and neurodegenerative diseases, and …

Cellular senescence in aging and age-related diseases: Implications for neurodegenerative diseases

EOW Gerdes, Y Zhu, BM Weigand, U Tripathi… - International review of …, 2020 - Elsevier
… Decreasing senescent cell abundance using … neurodegenerative diseases in preclinical
models. In this review, we consider roles of senescent cells in neurodegenerative diseases and …

Cellular senescence in brain aging and neurodegenerative diseases: evidence and perspectives

DJ Baker, RC Petersen - The Journal of clinical …, 2018 - Am Soc Clin Investig
… aging and neurodegenerative disease, suggesting … senescent cells in neurodegenerative
diseases, the mechanistic contribution of these cells that may actively drive neurodegeneration

Cellular senescence in the aging brain: a promising target for neurodegenerative diseases

MR Sahu, L Rani, R Subba, AC Mondal - Mechanisms of Ageing and …, 2022 - Elsevier
neurodegenerative diseases. This review summarizes the concept of cellular senescence, …
, and how it mediates neurodegeneration in several neurodegenerative disorders. Further, we …

Are there roles for brain cell senescence in aging and neurodegenerative disorders?

FCC Tan, ER Hutchison, E Eitan, MP Mattson - Biogerontology, 2014 - Springer
senescent state remains unclear. In this review we examine recent data that suggest that
cellular senescence … for many neurodegenerative diseases including Alzheimer’s disease (AD), …

Cellular senescence in neurodegenerative diseases

P Zhang, MH Sung - Cellular Senescence in Disease, 2022 - Elsevier
… Since the classification of cellular senescence has been … senescence in brain aging and
neurodegenerative diseases. A growing body of data documents evidence of senescence in …

Ageing as a risk factor for neurodegenerative disease

Y Hou, X Dan, M Babbar, Y Wei… - Nature Reviews …, 2019 - nature.com
… , cellular senescence, deregulated nutrient sensing, stem cell … of novel therapies for
neurodegenerative diseases are also … , mitophagy inducers and inhibitors of cellular senescence. …