Involvement of cytokines in normal CNS development and neurological diseases: recent progress and perspectives

B Zhao, JP Schwartz - Journal of neuroscience research, 1998 - Wiley Online Library
… In particular, we have highlighted recent work which supports a major role for the so-called
inflammatory cytokines and type 1 cytokines; factors including IL-1, IL-3, IL-6, TNF-, TGF-, and …

Systemic inflammation switches the inflammatory cytokine profile in CNS Wallerian degeneration

K Palin, C Cunningham, P Forse, VH Perry… - Neurobiology of disease, 2008 - Elsevier
… However, despite the prevalence of axon damage in neurological details of the inflammatory
responses, other stimuli that may influence its nature and the potential for deleterious …

Inflammation and the degenerative diseases of aging

PL McGEER, EG McGEER - Annals of the New York Academy …, 2004 - Wiley Online Library
inflammatory cytokines because these appear to be major actors in the inflammatory
phenomenon. … The inflammatory reaction in these degenerative neurological disorders could be …

Inflammatory process in Alzheimer's and Parkinson's diseases: central role of cytokines

Q Alam, M Zubair Alam, G Mushtaq… - Current …, 2016 - ingentaconnect.com
neurological disorders (NDs) characterized by degeneration of … Other notable cytokines
associated with neuroinflammation … pro-inflammatory cytokines, there are also cytokines such as …

Inflammatory process in Parkinson's disease: role for cytokines

T Nagatsu, M Sawada - Current pharmaceutical design, 2005 - ingentaconnect.com
… in the levels of proinflammatory cytokines, anti-apoptotic … pro-inflammatory cytokines,
anti-apoptotic neurotrophins and … around degenerative DA neurons release cytokines that may …

Cytokine networks in neuroinflammation

B Becher, S Spath, J Goverman - Nature Reviews Immunology, 2017 - nature.com
… However, prolonged exposure to pro-inflammatory cytokines … worsen or accelerate the
degenerative processes and tissue … to further inflammation, tissue destruction and neurological

Cytokines and chemokines at the crossroads of neuroinflammation, neurodegeneration, and neuropathic pain

G Ramesh, AG MacLean… - Mediators of inflammation, 2013 - Wiley Online Library
… posttraumatic inflammation and secondary degeneration by … The anti-inflammatory cytokine
IL-10 has been implicated in … Bb-induced inflammation may contribute to the neurologic and …

Inflammation in neurodegenerative diseases

S Amor, F Puentes, D Baker, P Van Der Valk - Immunology, 2010 - Wiley Online Library
… The presence of inflammatory cytokines and matrix … neurological disorders (PNND), neuronal
degeneration is directly … Here, we will briefly discuss models for the major neurological

Molecular inflammatory mediators in peripheral nerve degeneration and regeneration

CR Cámara-Lemarroy, FJ Guzmán-de la Garza… - …, 2010 - karger.com
cytokines [27] . IL10 mainly acts as an anti-inflammatory cytokine, while IL-6 is a pleiotropic
cytokine … back loop of inflammatory mediator production in the neural and nonneural cells that …

Microglia-mediated inflammation and neurodegenerative disease

L Xu, D He, Y Bai - Molecular Neurobiology, 2016 - Springer
… , while releasing the inflammatory cytokines to mediate inflammatory reaction. Activated
microglia … degeneration is a pathological hallmark of MS contributing to irreversible neurological