Effects of potent neutralizing antibodies from convalescent plasma in patients hospitalized for severe SARS-CoV-2 infection

A Gharbharan, CCE Jordans… - Nature …, 2021 - nature.com
… 300mL convalescent plasma containing high titers of neutralizing SARS-CoV-2 antibodies,
Convalescent plasma is safe, does not improve survival, has no effect on the disease course…

Convalescent plasma for COVID-19. A randomized clinical trial

A Gharbharan, CCE Jordans, C Geurtsvankessel… - MEDRxiv, 2020 - medrxiv.org
neutralizing antibody titers at hospital admission. Screening for antibodies and prioritizing
convalescent plasma … may benefit from convalescent plasma. Clinicaltrials.gov: NCT04342182 …

COVID-19 convalescent plasma is more than neutralizing antibodies: a narrative review of potential beneficial and detrimental co-factors

D Focosi, M Franchini, L Pirofski, T Burnouf… - Viruses, 2021 - mdpi.com
… COVID-19 convalescent plasma (CCP) is currently under … as specific antibodies, particularly
neutralizing antibodies, with clinical efficacy characterized according to the level or antibody

[HTML][HTML] Treatment for emerging viruses: Convalescent plasma and COVID-19

BL Brown, J McCullough - Transfusion and Apheresis Science, 2020 - Elsevier
… existing literature around convalescent plasma as a … mL convalescent plasma with
neutralizing antibody titers of >1:640. The median time from onset of illness to convalescent plasma

… plasma therapy for the treatment of patients with COVID‐19: assessment of methods available for antibody detection and their correlation with neutralising antibody …

H Harvala, ML Robb, N Watkins, S Ijaz… - Transfusion …, 2021 - Wiley Online Library
… of convalescent plasma donors as it can be performed at a BSL-2 facility. In the current
study, we have first determined the neutralising antibody levels in our convalescent plasma

Convalescent plasma for patients with COVID-19

F Zeng, X Chen, G Deng - Proceedings of the National …, 2020 - National Acad Sciences
… -CoV-2 neutralizing antibody titer in both studies. In … convalescent plasma with a neutralization
titer above 640 was transfused, while 400 mL convalescent plasma with a neutralization

[HTML][HTML] Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers, and convalescent plasma donors

C Zeng, JP Evans, R Pearson, P Qu, YM Zheng… - JCI insight, 2020 - ncbi.nlm.nih.gov
… cases tend to have higher neutralizing antibody titers (25) but also indicate that HCWs, as
well as convalescent plasma donors, have a varied neutralizing antibody response, which will …

Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

P Bégin, J Callum, E Jamula, R Cook, NM Heddle… - Nature medicine, 2021 - nature.com
… Each supplier had different criteria for qualifying convalescent plasma units that were based
on the presence of either viral neutralizing antibodies, measured by the plaque reduction …

Convalescent plasma to treat COVID-19: possibilities and challenges

JD Roback, J Guarner - Jama, 2020 - jamanetwork.com
… interferon, the use of convalescent plasma may have contributed to … In addition, the patients’
neutralizing antibody titers … , the 80 who received convalescent plasma had a lower mortality …

Neutralizing antibodies responses to SARS-CoV-2 in COVID-19 inpatients and convalescent patients

X Wang, X Guo, Q Xin, Y Pan, J Li, Y Chu, Y Feng… - MedRxiv, 2020 - medrxiv.org
… -19 convalescent patients can fully neutralize the cellular … of convalescent plasma containing
neutralizing antibody was … hypothesis that using convalescent plasma transfusion could …