… In general, the primary peak of viremia declines before the appearance of neutralizing
antibodies against HIV Env. HIV infected individuals may generate potent neutralizing antibodies …

… In contrast, our findings demonstrated that anti-gB antibodies have potent protection
capacity in-vivo, particularly when used as prophylaxis to limit infection. There are several …

… We also describe the roles that binding affinity, neutralizing activity, and protection provided
… inducing the production of highly potent and specific neutralizing antibodies. Analysis of the …

… effective protection against HIV-1, despite the potent action of CTLs. Some … that neutralizing
antibodies could provide effective protective activity, implying that the strategy of an antibody-…

… class of remarkably potent neutralizing antibodies such as PG9… of the most potent and broad
neutralizing anti-HIV antibodies … have 10-fold higher neutralizing potency than PG9, VRC01, …

… generation pipeline to rapidly screen more than 1800 antibodies, and established an animal
model to test protection. We isolated potent neutralizing antibodies (nAbs) to two epitopes …

… to treat or protect against global circulating viruses. Here we probed the neutralizing antibody
… with remarkably broad and potent neutralizing responses and rescued 17 new monoclonal …

… We therefore analyzed the in vivo protective efficacy of three potent neutralizing … despite
potent in vitro neutralizing activity against the challenge virus and high occupancy of antibody …

… neutralization profiles. Moreover, we identify four neutralizing antibodies that neutralize
all … A cocktail of these antibodies would likely provide robust protection from lethal SARS-CoV …

… work identifies neutralizing antibodies as an immune correlate of protection and provides a
quantitative prediction of the link between neutralizing antibody levels and clinical protection …