Influence of novel CD4 binding-defective HIV-1 envelope glycoprotein immunogens on neutralizing antibody and T-cell responses in nonhuman primates

I Douagi, MNE Forsell, C Sundling, S O'Dell… - Journal of …, 2010 - Am Soc Microbiol
… stimulated less potent neutralizing antibody activity against neutralization-sensitive viruses
… WT Env and primate CD4 on the generation of functional T cells and antibodies in response …

Development of a novel nonhuman primate model for Rift Valley fever

DR Smith, BH Bird, B Lewis, SC Johnston… - Journal of …, 2012 - Am Soc Microbiol
neutralizing antibody titers as early as day 7 pi (see Table S2 in the supplemental material).
By day 14 pi, all animals sampled developed neutralizing antibody … The animals exposed sc …

[HTML][HTML] Comparison of the immunogenicity & protective efficacy of various SARS-CoV-2 vaccine candidates in non-human primates

L Mukhopadhyay, PD Yadav, N Gupta… - Indian Journal of …, 2021 - journals.lww.com
Neutralizing antibody response: Different virus neutralization methods such as Plaque Reduction
and Neutralization … live virus neutralization assay, as well as pseudovirus neutralization

[HTML][HTML] Correlation between anthrax lethal toxin neutralizing antibody levels and survival in guinea pigs and nonhuman primates vaccinated with the AV7909 anthrax …

V Savransky, JD Shearer, MR Gainey, DC Sanford… - Vaccine, 2017 - Elsevier
… -induced toxin-neutralizing antibody (TNA) levels associated with the protection of animals
from lethal Bacillus anthracis challenge. Guinea pigs or nonhuman primates (NHPs) were …

Host immune responses to chronic adenovirus infections in human and nonhuman primates

R Calcedo, LH Vandenberghe, S Roy… - Journal of …, 2009 - Am Soc Microbiol
… of broadly reactive neutralizing antibodies to adenoviruses in … levels of serum neutralizing
antibodies, with adenovirus-… in humans compared to that in apes, which may contribute to …

Non-human primate immune libraries combined with germline humanization: an (almost) new and powerful approach for the isolation of therapeutic antibodies

T Pelat, P Thullier - MAbs, 2009 - Taylor & Francis
… searching for specific antibody activities, such as neutralization or signalling, and to avoid
any enhancing effect, which occurs when incompletely neutralizing antibodies increase the …

[HTML][HTML] COVID-19 research: lessons from non-human primate models

L Albrecht, E Bishop, B Jay, B Lafoux, M Minoves… - Vaccines, 2021 - mdpi.com
… They developed anti-spike IgGs and neutralizing antibodies, which were enhanced by
the second exposition to SARS-CoV-2. More recently, it was shown that relatively low …

Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates

AD Kirk, LC Burkly, DS Batty, RE Baumgartner… - Nature medicine, 1999 - nature.com
… monoclonal antibodies against B7 (ADK et al., manuscript in preparation). Therefore, it is
unlikely that hu5C8 is working solely by blocking B7 upregulation. Although antibody against …

Immunogenicity of clinically relevant SARS-CoV-2 vaccines in nonhuman primates and humans

PJ Klasse, DF Nixon, JP Moore - Science advances, 2021 - science.org
… for the induction of neutralizing antibodies (NAbs), while … antibody and T cell immune
response data derived from published studies of vaccines that were tested in nonhuman primates

Passive and active antibody studies in primates to inform HIV vaccines

AJ Hessell, DC Malherbe… - Expert review of vaccines, 2018 - Taylor & Francis
… to generate potent neutralizing antibodies. Expert commentary: Passive transfer studies
in nonhuman primates using human neutralizing monoclonal antibodies have informed the …