Naturally enhanced neutralizing breadth against SARS-CoV-2 one year after infection

Z Wang, F Muecksch, D Schaefer-Babajew, S Finkin… - Nature, 2021 - nature.com
… in affinity and breadth, we measured the relative affinity and neutralizing breadth of matched
SARS-CoV-2-neutralizing activity of the antibodies present at 1.3 or 12 months was not …

Neutralization breadth of SARS-CoV-2 viral variants following primary series and booster SARS-CoV-2 vaccines in patients with cancer

V Naranbhai, KJS Denis, EC Lam, O Ofoman… - Cancer cell, 2022 - cell.com
… to SARS-CoV-2 vaccines. We study the breadth of responses against SARS-CoV-2 variants
Neutralization of alpha, beta, gamma, and delta SARS-CoV-2 variants is impaired relative to …

The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2

H Xiong, H Sun, S Wang, L Yuan… - Proceedings of the …, 2022 - National Acad Sciences
SARS-CoV-2 neutralizing antibodies (nAbs). Here, we successfully generated a panel of
SARS-CoV-2/SARS-CoV cross-neutralizing … X17 offer broad neutralizing potential against most …

SARS-CoV-2 neutralizing antibodies: Longevity, breadth, and evasion by emerging viral variants

F Tea, A Ospina Stella, A Aggarwal… - PLoS …, 2021 - journals.plos.org
… longevity, polyantigenic breadth, and neutralization capacity of the SARS-CoV-2 antibody
… to globally emerging SARS-CoV-2 variants. Using 2 longitudinal SARS-CoV-2 community- …

Cross-neutralizing breadth and longevity against SARS-CoV-2 variants after infections

Y Kurahashi, S Sutandhio, K Furukawa… - Frontiers in …, 2022 - frontiersin.org
… Our results may reflect the increasing neutralizing breadth of antibodies which recognize
common epitopes among VOCs (46–48). Importantly, SARS-CoV-2 RNA and proteins were …

Increased potency and breadth of SARS-CoV-2 neutralizing antibodies after a third mRNA vaccine dose

F Muecksch, Z Wang, A Cho, C Gaebler, TB Tanfous… - BioRxiv, 2022 - biorxiv.org
… dose show increasing breadth and potency against pseudoviruses representing variants
that were not present in the vaccine. Finally, we compared the neutralization breadth of 3 rd …

[HTML][HTML] Development of potency, breadth and resilience to viral escape mutations in SARS-CoV-2 neutralizing antibodies

F Muecksch, Y Weisblum, CO Barnes, F Schmidt… - BioRxiv, 2021 - ncbi.nlm.nih.gov
neutralization potency against a panel of HIV-1 SARS-CoV-2 … known to confer resistance
to neutralization by individual human … Additionally, to determine the ability of the SARS-CoV-2 …

Broadly-neutralizing antibodies against emerging SARS-CoV-2 variants

LB Shrestha, N Tedla, RA Bull - Frontiers in immunology, 2021 - frontiersin.org
… of mAbs with strong neutralization breadth and potency. Despite variation in their VH
gene usage, all the above mAbs can effectively neutralize the emerging variants of SARS-COV-2. …

[HTML][HTML] Affinity maturation of SARS-CoV-2 neutralizing antibodies confers potency, breadth, and resilience to viral escape mutations

F Muecksch, Y Weisblum, CO Barnes, F Schmidt… - Immunity, 2021 - cell.com
neutralization potency, antibody evolution changed the mutational pathways for the acquisition
of viral resistance and restricted neutralization … the neutralization of circulating SARS-CoV-…

Temporal maturation of neutralizing antibodies in COVID-19 convalescent individuals improves potency and breadth to circulating SARS-CoV-2 variants

S Moriyama, Y Adachi, T Sato, K Tonouchi, L Sun… - Immunity, 2021 - cell.com
… of antibody maturation on durable neutralizing activity against original SARS-CoV-2 and …
after SARS-CoV-2 infection. Longitudinal evaluation of total RBD IgG and neutralizing antibody …