Anti-inflammatory effects of β-hydroxyisovalerylshikonin in BV2 microglia are mediated through suppression of the PI3K/Akt/NF-kB pathway and activation of the Nrf2 …

RGPT Jayasooriya, KT Lee, HJ Lee, YH Choi… - Food and Chemical …, 2014 - Elsevier
… β-HIVS has no impact on the viability of BV2 microglial cells In order to evaluate whether
β-HIVS would have a cytotoxic effect in BV2 microglial cells, we treated the cells with the …

Anthocyanins downregulate lipopolysaccharide-induced inflammatory responses in BV2 microglial cells by suppressing the NF-κB and Akt/MAPKs signaling pathways

JW Jeong, WS Lee, SC Shin, GY Kim, BT Choi… - International journal of …, 2013 - mdpi.com
… Activation of NF-κB is closely related to regulation of iNOS, COX-2, TNF-α, … BV2 cells;
therefore, we next investigated whether anthocyanins modulate the NF-κB activation in BV2 cells in …

Anti-inflammatory effects of isoalantolactone on LPS-stimulated BV2 microglia cells through activating GSK-3β-Nrf2 signaling pathway

M Wang, K Wang, X Gao, K Zhao, H Chen… - International …, 2018 - Elsevier
BV2 cells were cultured in 6 well plates and when the cells were grown to 50% confluent, it
was transiently transfected with siRNA-Nrf2 (100 nM, Santa Cruz, CA, USA) or control siRNA (…

Piceatannol attenuates lipopolysaccharide-induced NF-κB activation and NF-κB-related proinflammatory mediators in BV2 microglia

CY Jin, DO Moon, KJ Lee, MO Kim, JD Lee… - Pharmacological …, 2006 - Elsevier
NF-κB luciferase assay A total of 1 × 10 6 BV2 cells were transfected with 2 μg NF-κB-luciferase
reporter plasmids (BD Sciences, San Jose, CA) using lipofectamine according to the …

Quercetin inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglial cells by suppressing the NF-κB pathway and activating the Nrf2-dependent HO …

CH Kang, YH Choi, SK Moon, WJ Kim… - International …, 2013 - Elsevier
… Next, to assess the functional role of NF-κB in LPS-stimulated BV2 microglial cells, we
determined the expression levels of iNOS mRNA when pretreated with the specific NF-κB

Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells

HY Park, MH Han, C Park, CY Jin, GY Kim… - Food and chemical …, 2011 - Elsevier
… In order to exclude this possibility, MTT assays were performed in BV2 cellsNF-κB activation
in BV2 microglia cells by suppression of IκB degradation and nuclear translocation of NF-κB

[HTML][HTML] Activation of BV2 microglia by lipopolysaccharide triggers an inflammatory reaction in PC12 cell apoptosis through a toll-like receptor 4-dependent pathway

X Dai, N Li, L Yu, Z Chen, R Hua, X Qin… - Cell Stress and …, 2015 - Elsevier
cell model, the PC12 cells have been widely used. We hypothesized that TLR4/MyD88/NF-κB
signaling pathway may mediate the activation of BV2 … could participate in PC12 cell injury. …

Platycodin D inhibits β-amyloid-induced inflammation and oxidative stress in BV-2 cells via suppressing TLR4/NF-κB signaling pathway and activating Nrf2/HO-1 …

J Zhang, N Song, Y Liu, J Guo - Neurochemical Research, 2021 - Springer
… microglia cells through inhibition of LPS-induced NF-κB activation … the TLR4/NF-κB activation
in Aβ-stimulated BV-2 cells. … PLD in Aβ-stimulated BV-2 cells. These results indicated that …

Anti-inflammatory effects of arbutin in lipopolysaccharide-stimulated BV2 microglial cells

HJ Lee, KW Kim - Inflammation Research, 2012 - Springer
… Next, we examined the effect of arbutin on cell-to-matrix adhesion of BV2 cells. Under
LPS-induced inflammatory conditions, the adhesion of BV2 cells on gelatin, fibronectin, and …

β‐Sitosterol Alleviates Inflammatory Response via Inhibiting the Activation of ERK/p38 and NFκB Pathways in LPS‐Exposed BV2 Cells

Y Sun, L Gao, W Hou, J Wu - BioMed Research International, 2020 - Wiley Online Library
… Lipopolysaccharide (LPS) is a component of bacterial cell walls. Studies have … the cells [13,
14]. Therefore, LPS was used to stimulate BV2 cells to establish a microglia inflammation cell