MA Calzado, S Bacher… - Current medicinal …, 2007 - ingentaconnect.com
… the NFκB signaling system and the development and potential use of novel NF-κB inhibitors. … data show an important role of NFκB for the intiation and promotion phase of cancer. It will …
PP Tak, GS Firestein - The Journal of clinical investigation, 2001 - Am Soc Clin Investig
… of various NF-κB proteins, their role in inflammatorydisease, the regulation of NF-κB activity … IκB kinase (IKK), and the development of therapeutic strategies aimed at inhibition of NF-κB. …
T Zhang, C Ma, Z Zhang, H Zhang, H Hu - MedComm, 2021 - Wiley Online Library
… NF-κB on inflammation, … NF-κB for inflammatorydiseases and cancer treatment and the potential obstacles will be discussed. Further investigations on the precise functions of NF-κB in …
… NF-κB pathway as a target in cancer Despite the well-documented association of NF-κB with immune and inflammatorydisorders … NF-κB-activating cytokines, it is suggested that NF-κB …
… The notion that such a constitutive activity of NF-κB exerts … inflammatorydiseases have higher risks for cancer similar to immune-suppressed patients (see accompanying article). NF-κB …
… major activities of NF-kB proteins is controlling the inflammation process, which indicate that, they targeted the body's complex defense mechanisms under inflammationconditions. This …
M Karin - Cold Spring Harbor perspectives in biology, 2009 - cshperspectives.cshlp.org
… experimental evidence for the pathogenic function of NF-κB in cancer and discuss whether and how IKK-NF-κB targeted interventions can be used in cancer prevention and/or therapy. …
… , with the transcription factor NF-κB serving as the major lynchpin… NF-κB in linking inflammation to cancer. However, rather than providing a detailed summary of the inflammation-cancer …
S Wang, Z Liu, L Wang, X Zhang - Cellular & molecular immunology, 2009 - nature.com
… chronic inflammatorydisease (40-45). In Table 1, an outline is given of inflammation that has been associated with cancer development: skin inflammation with squamous cell carcinoma…