[HTML][HTML] Roles of NF-κB in cancer and inflammatory diseases and their therapeutic approaches

MH Park, JT Hong - Cells, 2016 - mdpi.com
… activity have also been shown to inhibit NF-κB. … functions of the NF-κB pathway, and the
role of NF-κB in cancer and inflammatory diseases, and the multitude of NF-κB inhibitors that …

NF-κB inhibitors for the treatment of inflammatory diseases and cancer

MA Calzado, S Bacher… - Current medicinal …, 2007 - ingentaconnect.com
… the NFκB signaling system and the development and potential use of novel NF-κB inhibitors.
… data show an important role of NFκB for the intiation and promotion phase of cancer. It will …

[HTML][HTML] NF-κB: a key role in inflammatory diseases

PP Tak, GS Firestein - The Journal of clinical investigation, 2001 - Am Soc Clin Investig
… of various NF-κB proteins, their role in inflammatory disease, the regulation of NF-κB activity
… IκB kinase (IKK), and the development of therapeutic strategies aimed at inhibition of NF-κB. …

NFκB signaling in inflammation and cancer

T Zhang, C Ma, Z Zhang, H Zhang, H Hu - MedComm, 2021 - Wiley Online Library
NF-κB on inflammation, … NF-κB for inflammatory diseases and cancer treatment and the
potential obstacles will be discussed. Further investigations on the precise functions of NF-κB in …

NFκB and the link between inflammation and cancer

JA DiDonato, F Mercurio, M Karin - Immunological reviews, 2012 - Wiley Online Library
NF-κB pathway as a target in cancer Despite the well-documented association of NF-κB with
immune and inflammatory disordersNF-κB-activating cytokines, it is suggested that NF-κB

[HTML][HTML] The complexity of NF-κB signaling in inflammation and cancer

B Hoesel, JA Schmid - Molecular cancer, 2013 - Springer
… The notion that such a constitutive activity of NF-κB exerts … inflammatory diseases have
higher risks for cancer similar to immune-suppressed patients (see accompanying article). NF-κB

[HTML][HTML] The Nuclear Factor Kappa B (NF-kB) signaling in cancer development and immune diseases

MR Zinatizadeh, B Schock, GM Chalbatani, PK Zarandi… - Genes & diseases, 2021 - Elsevier
… major activities of NF-kB proteins is controlling the inflammation process, which indicate that,
they targeted the body's complex defense mechanisms under inflammation conditions. This …

NF-κB as a critical link between inflammation and cancer

M Karin - Cold Spring Harbor perspectives in biology, 2009 - cshperspectives.cshlp.org
… experimental evidence for the pathogenic function of NF-κB in cancer and discuss whether
and how IKK-NF-κB targeted interventions can be used in cancer prevention and/or therapy. …

Inflammation meets cancer, with NF-κB as the matchmaker

Y Ben-Neriah, M Karin - Nature immunology, 2011 - nature.com
… , with the transcription factor NF-κB serving as the major lynchpin… NF-κB in linking inflammation
to cancer. However, rather than providing a detailed summary of the inflammation-cancer

NF-κB signaling pathway, inflammation and colorectal cancer

S Wang, Z Liu, L Wang, X Zhang - Cellular & molecular immunology, 2009 - nature.com
… chronic inflammatory disease (40-45). In Table 1, an outline is given of inflammation that has
been associated with cancer development: skin inflammation with squamous cell carcinoma