… In this work, we found that the membrane (M) protein of SARSCoV physically interacted
with IKKb using a coimmunoprecipitation assay (IPA). Expression of M suppressed tumor …

… and characterize SARS-CoV-2 proteins that were able to modulate NF-κB response and …
proteins of SARS-CoV-2 are NF-κB activators. No significant difference was found in NF-κB …

… SARS-CoV-2-induced inflammation is poorly understood. Here, we investigated direct
inflammatory functions of major structural proteins of SARS-CoV… activation of the NF-κB pathway in …

… of the IFN-I response, including PRR-mediated activation of NF-κB activation (19… Despite
the antagonistic potential of SARS-CoV-2, here we show that infection culminates in NF-κB …

… In this study, we screened 22 SARS-CoV-2 proteins for their ability to activate NF-κB …
induced NF-κB activation and increased IL-8 and IP-10 mRNA expression in a TAK1- and NF-κB …

… promoter through the activation of the NF-κB pathway. Our results suggest that SARS-CoV-2
skews the antiviral response in favor of an NF-κB-driven inflammatory response for which …

… between the SARS-CoV nucleocapsid (N) protein and NF-κB by … that the SARS-CoV N
protein can significantly activate NF-κB only in Vero E6 cells, which are susceptible to SARS-CoV …

… to the role that NF-κB activation plays in its … in NF-κB activation in the renin–angiotensin–aldosterone
system (RAAS) during severe acute respiratory syndrome coronavirus 2 (SARS-CoV…

… were dependent on NF-κB, which was activated through I-κBα degradation. These results
suggest that SARS-CoV spike protein may play an important role in the pathogenesis of SARS, …

… -CoV-2 infected cells. This NF-κB response was mediated by cGAS-STING activation and …
Our results show that SARS-CoV-2 directs a cGAS-STING mediated, NF-κB-driven …