… MAPKs) and nuclear transcription factor-kappa B (NF-kB) via receptor dimerization [11].
Activated MAPKs and components of the NF… on the TLR4, NF-kB, and MAPK signaling pathways. …

… property by down-regulated the expression of TLR4 up-regulated by LPS, thereby
attenuating TLR4 mediated the activation of NF-κB and MAPK signaling and the release of pro-…

… of TLR4 The expression of TLR4 will directly affect the downstream NF-κB and MAPK activation
in … Western blot was carried out to measure the activity of TLR4. The results showed that …

… Western-blotting was used to detect the activation of TLR4, MAPKs, IκBα, NF-κB p65, and …
inflammation via TLR4-mediated ROS-relative MAPK/NF-κB signaling pathways in VSMCs. …

… effect factors of TLR4-MAPK/NF-κB signaling pathways … TLR4-MAPK/NF-κB signaling
pathways. Furthermore, we used macrophage to clarify the effect of PSP on the TLR4-MAPK/NF-κB …

… Binding of LPS to TLR4 results in the activation of … factor-κB (NF-κB) and mitogen-activated
protein kinases (MAPKs). … via TLR4 abrogation mediated by the NF-κB and MAPK signaling …

… ) pathways transduce TLR4 signalling (Akira & Takeda 2004). In the MyD88-dependent
pathway, TLR4 signals recruit MyD88 to activate MAPKs or initiate NF-κB signalling, resulting in …

… the NF-κB activation induced by TLR4-… TLR4-TRAF6, MAPK and Akt pathways (10).
Previous data suggests that Res inhibits the inflammation via regulating the NF-κB, MAPKs, TLR4 …

… expression of TLR4 and MyD88, as well as some downstream effectors such as IRAK1,
TRAF6, and TAK1, which were involved in the activation of NF-κB and MAPK signaling pathways…

… In conclusion, activation of TLR4 in astrocytes induces signaling through NFκB, MAPK,
and Jak1/Stat1 pathways, which in turn regulate the expression of a wide range of …