Analysis of individuals from a dengue-endemic region helps define the footprint and repertoire of antibodies targeting dengue virus 3 type-specific epitopes

DV Andrade, LC Katzelnick, DG Widman, A Balmaseda… - MBio, 2017 - Am Soc Microbiol
… , consistent with the epidemiology of DENV in our cohort study in Nicaragua, where one
serotype predominantly circulates for several years at a time, could help explain the increase in …

Evaluation of the traditional and revised WHO classifications of dengue disease severity

F Narvaez, G Gutierrez, MA Pérez… - PLoS neglected …, 2011 - journals.plos.org
Dengue virus (DENV) infection leads to a range of outcomes, including subclinical infection,
… -based study of pediatric dengue in Managua, Nicaragua, we evaluated the traditional and …

Seroprevalence, risk factor, and spatial analyses of Zika virus infection after the 2016 epidemic in Managua, Nicaragua

JV Zambrana, F Bustos Carrillo… - Proceedings of the …, 2018 - National Acad Sciences
… ZIKV is related to other flaviviruses of public health concern, including yellow fever and West
Nile viruses, and is most closely related to dengue virus (DENV). The antibody response to …

Distinguishing patients with laboratory-confirmed chikungunya from dengue and other acute febrile illnesses, Puerto Rico, 2012–2015

LI Alvarado, OD Lorenzi… - PLoS Neglected …, 2019 - journals.plos.org
… We enrolled 8,996 AFI patients and tested for CHIKV, dengue viruses 1–4 (DENV 1–4),
and other pathogens. A pathogen was detected in 55% of participants; 18.2% had CHIKV and …

Economic and disease burden of dengue in Mexico

EA Undurraga, M Betancourt-Cravioto… - PLoS neglected …, 2015 - journals.plos.org
… With this study, Mexico joins Panama, Puerto Rico, Nicaragua, and Thailand as the only
countries or areas worldwide with comprehensive (illness and preventive) empirical estimates of …

Effect of prior Zika and dengue virus exposure on the severity of a subsequent dengue infection in adults

BM Valencia, PC Sigera, P Weeratunga, N Tedla… - Scientific Reports, 2022 - nature.com
… Given the structural similarity between Zika and dengue viruses, prior infection from one
virus is hypothesized to modulate the severity of a subsequent infection from the other virus. A …

CD14+CD16+ monocytes are the main target of Zika virus infection in peripheral blood mononuclear cells in a paediatric study in Nicaragua

D Michlmayr, P Andrade, K Gonzalez… - Nature …, 2017 - nature.com
… The gene expression profile in monocytes isolated from ZIKV- and dengue virus-infected
patients was comparable, except for significant differences in interferon-γ, CXCL12, XCL1, …

Elevated levels of total and dengue virus‐specific immunoglobulin E in patients with varying disease severity

P Koraka, B Murgue, X Deparis… - Journal of medical …, 2003 - Wiley Online Library
dengue virus infected patients had a primary dengue virus infection (mean IgM/IgG ratio, 6.8)
and 127 patients had a secondary dengue virusdengue in the 1998 epidemic in Nicaragua

[HTML][HTML] Human genetic determinants of dengue virus susceptibility

LL Coffey, E Mertens, AC Brehin… - Microbes and …, 2009 - Elsevier
Dengue virus (DENV) is an emerging mosquito-borne pathogen that produces significant
morbidity worldwide resulting in an estimated 50–100 million infections annually. DENV …

[HTML][HTML] Frequency of Dengue Virus-Specific T Cells is related to Infection Outcome in Endemic Settings

RI Gálvez, A Martínez-Pérez, EA Escarrega, T Singh… - medRxiv, 2024 - ncbi.nlm.nih.gov
Dengue is widespread in tropical and subtropical regions globally and leads to a considerable
burden of disease. Annually, dengue virus (… in dengue-endemic Managua, Nicaragua. We …