… Introduction: Dengue virus (DENV) infection is currently a major cause of morbidity in the
world, and its incidence has mainly increased during the last years in Latin America, including …

… Samples from participants 2–14 years old were obtained through the ongoing PDCS,
originally established in 2004 to study dengue and dengue virus infections in Nicaragua [17, 18] …

… of the severe dengue syndromes—the continuum of dengue haemorrhagic fever and dengue
shock syndrome—is well defined. One of the results of the focus on dengue haemorrhagic …

… incidence reported in the longitudinal cohorts with sufficient data (Nicaragua, Peru, Thailand,
… In Nicaragua and Peru, the seroprevalence in the population was high, with most children …

… Dengue virus infection causes a spectrum of illness ranging from asymptomatic cases to
dengue hemorrhagic fever/dengue … in 1994 it was isolated in Nicaragua, and later reported in …

… dengue virus infection and replication: in vitro, in a human megakaryocyte cell line with viral
… We conclude that megakaryocytes can produce dengue viruses in the bone marrow niche, …

… virus in the Flaviviridae family, genus flavivirus, that occurs as one of four serotypes [2].
Dengue viruses are closely related to Zika virus (… Data from a Nicaraguan pediatric cohort has …

… disease caused by infection with dengue virus (DENV) that … with recent reports of adult dengue
patients in Singapore and Vietnam, … A recent report in pediatric patients in Nicaragua also …

… It was first detected in Nicaragua and Panama, … of dengue viruses, the continuous circulation
of all four virus serotypes, and the persistence of large numbers of cases of classic dengue …

… caused by one of four dengue viruses (DENV-1, DENV-2… dengue virus can cause a
spectrum of illness ranging from no symptoms to life-threatening dengue haemorrhagic fever/dengue …