DM Salerno, DL Jennings, NW Lange… - American Journal of …, 2022 - Wiley Online Library
… but excluded individuals with a history of prior COVID-19 or vaccination. The incidence of … the nirmatrelvir/ritonavir EUA. This is in line with higher rates of hospitalization for COVID-19 in …
A Evans, C Qi, JO Adebayo, J Underwood, J Coulson… - Journal of Infection, 2023 - Elsevier
… the effectiveness of sotrovimab, molnupiravir, and nirmatrelvir-ritonavir in preventing hospital admission and death in higher-risk patients (Fig. 1) with COVID-19 in Wales, UK, during the …
J Buxeraud, S Faure, É Fougere - Actualités pharmaceutiques, 2022 - Elsevier
Nirmatrelvir-ritonavir (Paxlovid®), a treatment for Covid-19 The nirmatrelvir-ritonavir (Paxlovid®) is a treatment against Covid-19 available in pharmacies since February 4, 2022. …
J Hammond, RJ Fountaine, C Yunis… - … England Journal of …, 2024 - Mass Medical Soc
… The median time to sustained alleviation of all targeted signs and symptoms of Covid-19 was 12 days in the nirmatrelvir–ritonavir group and 13 days in the placebo group (P=0.60). Five …
… Nirmatrelvir inhibits a protease enzyme produced by SARS-CoV-2 that is necessary for viral replication. Low-dose ritonavir is combined with nirmatrelvir as a … Ritonavir is an inhibitor of …
LE Wee, AT Tay, C Chiew, BE Young, B Wong… - Clinical Microbiology …, 2023 - Elsevier
… Utilizing a multivariable Cox model with time-updated exposure to nirmatrelvir/ritonavir, nirmatrelvir/ritonavir was associated with a reduction in the hazard of COVID-19 hospitalization (…
… In this work, we compare efficacy of molnupiravir and nirmatrelvir/ritonavir in the Roborovski dwarf hamster model of severe COVID-19-like viral pneumonia and the ferret transmission …
MH Chuang, JY Wu, TH Liu, WH Hsu… - Journal of Medical …, 2023 - Wiley Online Library
… of nirmatrelvir plus ritonavir (NMV-r) on post-acute COVID-19 … We identified nonhospitalized adult patients with COVID-19 … and a composite of post-COVID-19 symptoms according to the …