Management and outcome of COVID-19 infection using nirmatrelvir/ritonavir in kidney transplant patients

P Giguère, MJ Deschenes, MK Van Loon… - Clinical Journal of the …, 2023 - journals.lww.com
… who received nirmatrelvir/ritonavir was conducted. We included eligible kidney transplant
recipients who developed COVID-19 and were treated with nirmatrelvir/ritonavir from March 31…

Pharmacokinetics of nirmatrelvir and ritonavir in COVID-19 patients with end-stage renal disease on intermittent hemodialysis

T Lingscheid, M Kinzig, A Krüger, N Müller… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
… of nirmatrelvir/ritonavir (150 mg/100 mg twice a day) in four patients with ESRD undergoing
hemodialysis. Nirmatrelvir … and hepatic tolerance of nirmatrelvir and ritonavir treatment in four …

Evaluating the risk of drug-drug interactions with pharmacokinetic boosters: the case of ritonavir-enhanced nirmatrelvir to prevent severe COVID-19

F Girardin, O Manuel… - Clinical …, 2022 - clinicalmicrobiologyandinfection …
… ]; nirmatrelvir (NMV) combined with ritonavir (NMV/r) is assessed in phase 3 trials as an
early therapeutic agent for patients at risk for COVID-19-related complications. Data supporting …

Effectiveness of nirmatrelvir-ritonavir for the treatment of patients with mild to moderate COVID-19 and at high risk of hospitalization: systematic review and meta …

KM Souza, G Carrasco, R Rojas-Cortés… - Plos one, 2023 - journals.plos.org
… The results were valid in vaccinated or unvaccinated high-risk individuals with COVID-19.
Data … and safety of nirmatrelvir-ritonavir and help improve treatment guidelines for COVID-19. …

Optimizing the use of nirmatrelvir/ritonavir in solid organ transplant recipients with COVID-19: a review of immunosuppressant adjustment strategies

Y Tang, Y Li, T Song - Frontiers in Immunology, 2023 - frontiersin.org
… evaluate the use and adverse effects of nirmatrelvir/ritonavir in SOTRs and explore feasible
… suggest that nirmatrelvir/ritonavir could be a feasible treatment option for COVID-19 in SOTRs…

Nirmatrelvir/ritonavir and risk of long COVID symptoms: a retrospective cohort study

S Congdon, Z Narrowe, N Yone, J Gunn, Y Deng… - Scientific reports, 2023 - nature.com
… Multivariable logistic regression models controlled for age, sex, race/ethnicity, chronic
conditions, and COVID-19 vaccination status. We found that participants who took …

Nirmatrelvir-ritonavir for COVID-19

EG McDonald, TC Lee - Cmaj, 2022 - Can Med Assoc
… Treatment should start as soon as possible after a confirmed diagnosis of COVID-19,
ideally within 5 days of symptom onset. Although observational safety data for ritonavir in …

Optimizing COVID-19 treatment in immunocompromised patients: early combination therapy with remdesivir, nirmatrelvir/ritonavir and sotrovimab

I Gentile, M Foggia, M Silvitelli, A Sardanelli… - Virology Journal, 2023 - Springer
COVID-19 patients, 18 of which received a complete combination of two antivirals (remdesivir
plus nirmatrelvir/ritonavir or … patient treated with a combination of nirmatrelvir/ritonavir (N/r) …

Nirmatrelvirritonavir and viral load rebound in COVID-19

AS Anderson, P Caubel… - New England Journal of …, 2022 - Mass Medical Soc
… Patients received nirmatrelvir (300 mg) plus ritonavir (100 mg) or placebo every 12 hours
for 5 days. Over an average of 27 days, the patients in the nirmatrelvirritonavir group had a …

[HTML][HTML] Clinical characteristics of COVID-19 rebound after nirmatrelvir-ritonavir or molnupiravir therapy: A prospective cohort study

J Han, S Bae, J Jung, MJ Kim, YP Chong, SO Lee… - Medicine, 2023 - journals.lww.com
… “true” incidence of COVID-19 rebound between the nirmatrelvir-ritonavir and molnupiravir
… medications that interact with nirmatrelvir-ritonavir were administered molnupiravir instead. …