… tissues, which was linked to metastasis, invasion, larger tumor size, and poor prognosis.
This study found that NLRP3 likely governs CRC metastasis by activating the EMT, suggesting …

… To explore the expression of NLRP3 in colorectal cancer tissues, we used IHC to detect
NLRP3 expression in 25 sets of CRC tissues and adjacent normal tissues. We found that NLRP3 …

… in Nlrp3 inflammasome components had exacerbated liver colorectal cancer metastatic
growth, … of differential cancer cell colonization or proliferation, intestinal microbiota effects, or …

… , NLRP3-/mice had greater weight loss and inflammation score, and the lack of other
inflammasome … , indicating that the NLRP3 inflammasome retards colon tumors. Other studies …

… of NLRP3-mediated EMT and the grade of colorectal cancer. … -β, NLRP3, and NLRP3
inflammasome complex in mediating … in the migration and metastasis of colorectal cancer cells (20)…

… to promote the invasion and migration of colorectal cancer cells by regulating epithelial–…
NLRP3 inflammasome as a potential therapeutic target to prevent metastatic colorectal cancer…

… NLRP3 expression, not the inflammasome activation, was required for EMT in colorectal cancer
… one of pivotal steps in colorectal cancer cell invasion and metastasis, by which epithelial …

… and metastasis of breast cancer [34]. Moreover, activation of NLRP3 inflammasomes promoted
tumor metastasis of … between NLRP3 expression and TNM stage, distant metastasis and …

… colorectal cancer via NLRP3 inflammasome activation in vitro and in vivo. NLRP3 chimeric
mice harboring orthotopic tumors … gingivalis in predicting colorectal cancer recurrence and …

… tumors was higher in NLRP3 mice [37]. The study regarding the correlation between NLRP3
inflammasomes and colorectal cancer metastasis … of NLRP3 inflammasomes components, …