Oral nirmatrelvir for high-risk, nonhospitalized adults with Covid-19

J Hammond, H Leister-Tebbe, A Gardner… - … England Journal of …, 2022 - Mass Medical Soc
… trial in which symptomatic, unvaccinated, nonhospitalized adults at high risk for progression
to … Molnupiravir is an orally administered antiviral Covid-19 treatment that currently has …

Real-world effectiveness of oral antivirals for COVID-19

C Burdet, F Ader - The Lancet, 2022 - thelancet.com
Molnupiravir and nirmatrelvir plus ritonavir were granted an emergency … for treating outpatients
with first-ever SARS-CoV-2 infection confirmed by PCR (aged ≥18 years for molnupiravir

Why molnupiravir fails in hospitalized patients

AN Brown, Y Lang, J Zhou, EJ Franco, KC Hanrahan… - Mbio, 2022 - Am Soc Microbiol
molnupiravir is currently only available under emergency use authorization for the treatment
of adults … Here, we explained why molnupiravir failed for the treatment of COVID-19 in …

Real-world effectiveness of molnupiravir and nirmatrelvir/ritonavir among COVID-19 inpatients during Hong Kong's Omicron BA. 2 wave: an observational study

CKH Wong, ICH Au, KTK Lau, EHY Lau, BJ Cowling… - medRxiv, 2022 - medrxiv.org
non-hospitalized adults with COVID-19. While no clinical benefits have been observed with
molnupiravir … early (i) molnupiravir or (ii) nirmatrelvir/ritonavir treatment at public hospitals …

Nirmatrelvir for vaccinated or unvaccinated adult outpatients with Covid-19

J Hammond, RJ Fountaine, C Yunis… - … England Journal of …, 2024 - Mass Medical Soc
treatment for mild-to-moderate coronavirus disease 2019 (Covid-19). The efficacy of this
treatment in … safety of nirmatrelvir–ritonavir in nonhospitalized adults with symptomatic Covid-19 …

Incidence of viral rebound after treatment with nirmatrelvir-ritonavir and molnupiravir

GLH Wong, TCF Yip, MSM Lai, VWS Wong… - JAMA Network …, 2022 - jamanetwork.com
… of COVID-19 in nonhospitalized patients.  … Meaning In this study, viral rebound was
uncommon in adults with COVID-19 after treatment with nirmatrelvir-ritonavir and molnupiravir, …

The benefits of molnupiravir treatment in healthcare facilities patients with COVID-19

SL Cheng, PH Wang, CY Chang… - Drug Design …, 2023 - Taylor & Francis
… risk reduction of hospitalization or mortality in non-hospitalized patients infected with mild-to…
treatment with MOL reduced the risk of hospitalization or death in at-risk, unvaccinated adults

Molnupiravir in COVID-19: A systematic review of literature

AK Singh, A Singh, R Singh, A Misra - Diabetes & Metabolic Syndrome …, 2021 - Elsevier
Molnupiravir initially emerged as a possible treatment of influenza viruses, encephalitic …
to assess efficacy and safety of molnupiravir in 1850 non-hospitalized adult (18 years or older) …

Comparative effectiveness of Paxlovid versus sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in non-hospitalised patients: observational …

B Zheng, J Tazare, L Nab, A Mehrkar, B MacKenna… - medRxiv, 2023 - medrxiv.org
… of severe outcomes between Paxlovid users and those treated with molnupiravir [10] (a
third-line … We conducted a population-based cohort study with all adults (≥18 years old) within …

Clinical Outcome and 7-Day Virological Clearance in High-Risk Patients with Mild–Moderate COVID-19 Treated with Molnupiravir, Nirmatrelvir/Ritonavir, or …

F Bai, T Beringheli, V Vitaletti, A Santoro, F Molà… - Infectious Diseases and …, 2024 - Springer
Introduction We compared the effectiveness and virological clearance (VC) at day 7 (T7)
post-treatment with molnupiravir, nirmatrelvir/ritonavir, and remdesivir in SARS-CoV-2-infected …