Oral nirmatrelvir for high-risk, nonhospitalized adults with Covid-19

J Hammond, H Leister-Tebbe, A Gardner… - … England Journal of …, 2022 - Mass Medical Soc
… -daily administration of 300 mg of nirmatrelvir plus 100 mg of … 90% effective concentration
of nirmatrelvir (ie, the concentration … of nirmatrelvir plus ritonavir in nonhospitalized adults with …

Oral nirmatrelvir and ritonavir for coronavirus disease 2019 in vaccinated, nonhospitalized adults aged 18–50 years

JS Faust, A Kumar, J Shah, S Khadke… - Clinical Infectious …, 2023 - academic.oup.com
… The effects of nirmatrelvir/ritonavir (NMV/r [Paxlovid]) on coronavirus disease 2019 (COVID-…
adults are unclear. The objective of this study was to assess if NMV/r use in vaccinated adults

Nirmatrelvir–remdesivir association for non-hospitalized adults with COVID-19, point of view

F Ferrara, A Zovi, U Trama, A Vitiello - Inflammopharmacology, 2022 - Springer
… The new oral antiviral paxlovid consists of two active drugs: nirmatrelvir (PF-07321332), which
acts … of HIV, used to slow the metabolism of nirmatrelvir. Paxlovid is authorized in 150 mg …

Oral nirmatrelvir and ritonavir in nonhospitalized vaccinated patients with coronavirus disease 2019

S Ganatra, SS Dani, J Ahmad, A Kumar… - Clinical Infectious …, 2023 - academic.oup.com
… Treatment of coronavirus disease 2019 (COVID-19) with nirmatrelvir plus ritonavir (NMV-r)
in high-risk nonhospitalized unvaccinated patients reduced the risk of progression to severe …

COVID-19 treatments approved in the European Union and clinical recommendations for the management of non-hospitalized and hospitalized patients

S Bellino - Annals of medicine, 2022 - Taylor & Francis
… or remdesivir in non-hospitalized patients with mild-… nirmatrelvir/ritonavir, 30% for molnupiravir,
and 87% for remdesivir, respectively [Citation24]. Therefore, in this setting oral nirmatrelvir

Effectiveness of nirmatrelvir/ritonavir and molnupiravir in non-hospitalized adults with COVID-19: systematic review and meta-analysis of observational studies

YM Mesfin, JE Blais, KT Kibret… - Journal of …, 2024 - academic.oup.com
… the effectiveness of nirmatrelvir/ritonavir and molnupiravir versus no oral antiviral treatment
in reducing severe clinical outcomes among non-hospitalized adults stratified by their COVID-…

[PDF][PDF] Nirmatrelvir for nonhospitalized adults with Covid-19

BS Chen, CH Hung, JCC Wei - NEW ENGLAND JOURNAL OF …, 2022 - researchgate.net
… To the Editor: Nirmatrelvir is a promising orally administered antiviral agent against … nirmatrelvir
treatment foundational to their Covid-19 strategy.Ideally, early treatment with nirmatrelvir (…

[HTML][HTML] Current status of oral antiviral drug treatments for SARS-CoV-2 infection in non-hospitalized patients

DV Parums - … science monitor: international medical journal of …, 2022 - ncbi.nlm.nih.gov
… three pills (two of nirmatrelvir and one of ritonavir) … nirmatrelvir/ritonavir (Paxlovid ® ) is still
awaited. The first regulatory approvals of molnupiravir and nirmatrelvir/ritonavir as the first oral

Nirmatrelvir for vaccinated or unvaccinated adult outpatients with Covid-19

J Hammond, RJ Fountaine, C Yunis… - … England Journal of …, 2024 - Mass Medical Soc
Nirmatrelvir is an orally administered antiviral agent that … with at least one risk factor for
severe Covid-19, nirmatrelvir–… and safety of nirmatrelvir–ritonavir in nonhospitalized adults with …

[HTML][HTML] Real-world effectiveness of early molnupiravir and nirmatrelvir/ritonavir among hospitalized, non-oxygen-dependent COVID-19 patients on admission during …

CK Wong, IC Au, KT Lau, EH Lau, BJ Cowling… - 2022 - europepmc.org
… and virologic outcomes associated with molnupiravir and nirmatrelvir/ritonavir use in COVID-…
While both oral antivirals are now indicated for non-hospitalized COVID-19 patients who are …