… binding helps stabilize the capsid lattice as it passes through the central channel of the
NPC. Recent studies have indicated that the capsid could remain at the nuclear pore for a few …

… of the capsid lattice occurs or whether the lattice “opens” to … that the capsid shell of HIV was
lost early after cell entry (… targets the CA lattice, for approximately an hour after cell entry [13]. …

… To assess the stress impact of the spatially confined environment of the NPC central
channel on the capsid structural state, we characterized the capsid lattice order using neighbor-…

… capsid lattice flexibility for nuclear entry. In conclusion, we hypothesise that during a productive
infection, a capsid remodelling step takes place at the nuclear … uncoating, or capsid lattice …

… Facilitating nucleoplasmic transport to specific subnuclear regions: Coating the capsid
lattice with CPSF6 upon nuclear entry leads to targeting of the subviral structure to nuclear …

… capsids cluster in the nucleus in a dose-dependent manner, suggesting that they may have
followed a common entry route … However, HIV-1 CA or the capsid lattice was found to directly …

… nuclear entry in target cells, underscoring a wide range of functional requirements for the CA
protein and/or capsid lattice … of virion-associated CA appears to be lost soon after entry (21…

… Some capsid is detected in the nucleus but it is unclear if it has any function. We … capsid
mutation confers resistance to C-A1, suggesting that capsid might affect post-nuclear entry steps. …

… nuclear translocation. Thus, the multimeric CA complexes lead the viral genome into the host
nuclear … main discoveries to date that uncover the viral capsid as a key player in the reverse …

… disassembly of the CA-lattice, followed by physical separation … capsid may not be removed
before nuclear entry or that it may even play a role in helping the virus get inside the nucleus…