… build DNA-origami-based NPC mimics to study the mechanism of HIV-1 nuclear transport. …
In this study, we model HIV-1 nuclear entry using NPC-mimicking DNA-origami channels and …

… of the nuclear membrane. Here we realize active nuclear import of DNA origami objects
in … We developed a custom DNA origami single-strand scaffold featuring a mammalian-cell …

… Here, we use DNA-origami mimics of the NPC, termed NuPODs (NucleoPorins Organized
by DNA), to reveal the mechanistic underpinnings of HIV-1 capsid nuclear entry. We found …

… and subsequent entry has been rarely explored. Here, we describe the use of DNA origami
… by virtue of the convenience and precision of DNA origami nanoboxes (DONs) to tailor their …

… could be delivered to the cell and also that addition of a nuclear localization sequence to
the DNA origami resulted in it being delivered to the nucleus, something only seen in cell …

… DNA origami is a promising … DNA-origami design and internalization efficiency in
different cancer cell lines remains elusive. We investigated the cellular uptake of four DNA-origami …

… molecular traffic between the nucleus and cytoplasm. To … , we built a DNA-origami NanoTrap.
The NanoTrap comprises … Finally, we demonstrated that the nuclear transport receptor, …

… Here, we build DNA nanopores with programmable diameters and nup arrangement to …
nup assemblies and mediating the nuclear entry of viruses. Nuclear pore complexes (NPCs) – …

… , as shown by the rapid enhanced intensity of Cy3-labeled DNA strands in acidic PBS …
the nuclear pores, it was easily degraded in lysosomal environment before its entry to nucleus, …

The nascent field of DNA nanotechnology has undergone rapid growth since its inception.
By using DNA as a biologically “safe” material, DNA nanotechnology shows great promise in …