Framework nucleic acids in nuclear medicine imaging: shedding light on nano–bio interactions

H Wang, Q Liu, X Lan, D Jiang - … Chemie International Edition, 2022 - Wiley Online Library
Nuclear imaging of FNAs in the form of DNA origami nanostructures showed preferential
renal accumulation, leading to efficient alleviation of acute kidney injury in mice. Zhao and co-…

Understanding the fate of DNA nanostructures inside the cell

CM Green, D Mathur, IL Medintz - Journal of Materials Chemistry B, 2020 - pubs.rsc.org
… (a) Schematic depiction and corresponding TEM image of a DNA origami rod discretely …
of the DNA origami rod was suspected to occur. (c–f) TEM visualization of DNA nanostructures …

A coarse-grained model for DNA origami

RV Reshetnikov, AV Stolyarova… - Nucleic acids …, 2018 - academic.oup.com
DNA origami structure and dynamics. The tool is based on a novel coarse-grained model
dedicated to geometry optimization and conformational analysis of DNA origami. … DNA origami

The potential of DNA origami to build multifunctional materials

K Tapio, I Bald - Multifunctional Materials, 2020 - iopscience.iop.org
… (b) Left: schematic view of DNA origami cylinder mimicking nuclear pore complex. The ssDNA
handles (red helices) are used to anchor the FG-nups. Left: schematic depictions and TEM …

Fabricating higher-order functional DNA origami structures to reveal biological processes at multiple scales

Y Zhou, J Dong, Q Wang - NPG Asia Materials, 2023 - nature.com
… nanotrap was constructed to study the selective filtering capability of the nuclear pore
complex. Molecular bites were preanchored at the bottom of the trap, and FG-Nups formed a …

[HTML][HTML] Piggybacking functionalized DNA nanostructures into live cell nuclei

GM Roozbahani, P Colosi, A Oravecz, EM Sorokina… - bioRxiv, 2024 - ncbi.nlm.nih.gov
… We found this piggybacking approach is size dependent, with no clear nuclear delivery
observed using a larger size DNA origami (~4.8 MDa, ~90 nm long nanorod), while the …

Supramolecular DNA origami nanostructures for use in bioanalytical applications

S Kogikoski Jr, WJ Paschoalino, LT Kubota - TrAC Trends in Analytical …, 2018 - Elsevier
DNA origami nanogear formed from V-shaped DNA origami subunits … B) DNA origami canvas
array showing the formation of a … rings with disordered proteins, mimicking the nuclear pore …

Folate-functionalized DNA origami for targeted delivery of doxorubicin to triple-negative breast cancer

S Pal, T Rakshit - Frontiers in Chemistry, 2021 - frontiersin.org
… structures for 6, 12, and 24 h respectively, suggesting a higher cellular uptake with increasing
time; Cell nucleus and membrane were stained with Hoechst® 33342 (blue) and wheat …

[图书][B] High Force Applications of DNA Origami Devices

MA Darcy - 2021 - search.proquest.com
… After being transported across the cell membrane, the DNA origami device is brought to
the nucleus before degradation enables the efflux pumps to export the theraputic agent …

Visualization of the hepatic and renal cell uptake and trafficking of tetrahedral DNA origami in tumour

S Zhu, H Peng, H Kong, Q Yan, K Xia, L Wang… - Cell …, 2024 - Wiley Online Library
… Visualization of the cellular uptake and trafficking of DNA origami … Receptor-mediated
entry of pristine octahedral DNA … Enhanced functional properties of three DNA origami