The nucleocapsid protein of SARSCoV-2: a target for vaccine development

NK Dutta, K Mazumdar, JT Gordy - Journal of virology, 2020 - Am Soc Microbiol
… is important for eliciting antibodies against SARS-CoV during the immune response …
SARSCoV-2 nucleocapsid protein is similar to those of previously described coronavirus N proteins

The SARS-CoV nucleocapsid protein: a protein with multifarious activities

M Surjit, SK Lal - Infection, genetics and evolution, 2008 - Elsevier
… Structure of the SARS-CoV nucleocapsid protein. A schematic diagram showing various
different domains identified to-date. The numbers 1–422 correspond to the length in amino …

Biochemical characterization of SARS-CoV-2 nucleocapsid protein

W Zeng, G Liu, H Ma, D Zhao, Y Yang, M Liu… - Biochemical and …, 2020 - Elsevier
… RNA binding domain of nucleocapsid phosphoprotein from SARS coronavirus 2 (PDB:
6M3M.1.… the structure of SARS Coronavirus Nucleocapsid Protein (PDB: 2CJR.1.A) as a template. …

[HTML][HTML] Crystal structure of SARS-CoV-2 nucleocapsid protein RNA binding domain reveals potential unique drug targeting sites

S Kang, M Yang, Z Hong, L Zhang, Z Huang… - … Pharmaceutica Sinica B, 2020 - Elsevier
… Further comparison with mild virus type HCoV-… of SARS-CoV-2 nucleocapsid protein N-terminal
domain, guiding the design of novel antiviral agents specific targeting to SARS-CoV-2. …

The SARS coronavirus nucleocapsid protein–forms and functions

C Chang, MH Hou, CF Chang, CD Hsiao, T Huang - Antiviral research, 2014 - Elsevier
… from porcine reproductive and respiratory syndrome virus (PRRSV), … nucleocapsid protein
in both SARS-CoV and PRRSV. The structural similarity between the N proteins of SARS-CoV

Identification and functional analysis of the SARS-COV-2 nucleocapsid protein

T Gao, Y Gao, X Liu, Z Nie, H Sun, K Lin, H Peng… - BMC microbiology, 2021 - Springer
… with SARS-COV-2 N protein … of SARS-COV-2 N protein predicted a total number of 12
phosphorylated sites and 9 potential protein kinases which would significantly affect SARS-COV-…

The ORF6, ORF8 and nucleocapsid proteins of SARS-CoV-2 inhibit type I interferon signaling pathway

JY Li, CH Liao, Q Wang, YJ Tan, R Luo, Y Qiu, XY Ge - Virus research, 2020 - Elsevier
… been conducted on SARS-CoV-2. In this study, we screened the viral proteins of SARS-CoV-2
and found that the viral ORF6, ORF8 and nucleocapsid proteins were potential inhibitors …

Structures of the SARSCoV2 nucleocapsid and their perspectives for drug design

Y Peng, N Du, Y Lei, S Dorje, J Qi, T Luo, GF Gao… - The EMBO …, 2020 - embopress.org
… of the SARS-CoV-2 N protein … of SARS-CoV-2 and other coronaviruses, SARS-CoV-2 has
a genome organization similar to that of SARS-CoV (Fig 1A), and the SARS-CoV-2 N protein

SARSCoV2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs

TM Perdikari, AC Murthy, VH Ryan, S Watters… - The EMBO …, 2020 - embopress.org
nucleocapsid protein (N) from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
condenses with RNA via liquid–liquid phase separation (LLPS) and that N protein can be …

The SARS-CoV-2 nucleocapsid protein and its role in viral structure, biological functions, and a potential target for drug or vaccine mitigation

Z Bai, Y Cao, W Liu, J Li - Viruses, 2021 - mdpi.com
… with SARS CoV-2 also exhibited the same phenomenon and SARS CoV-2 N protein can …
In the initiation step, the dsRNA in infected cells could be sequestrated by the N protein, …