[HTML][HTML] SARS-coV-2 treatment approaches: numerous options, no certainty for a versatile virus

S Iacob, DG Iacob - Frontiers in Pharmacology, 2020 - frontiersin.org
… Still, the pathogenic mechanisms behind SARS-CoV-2 have … of ACE2 receptors or SARS-CoV-2
spike protein epitopes, … with numerous drugs with unproven effect against SARS-CoV-2 …

Lessons from SARSCoV, MERS‐CoV, and SARSCoV‐2 Infections: What We Know So Far

RT Alsafi - Canadian Journal of Infectious Diseases and …, 2022 - Wiley Online Library
… in their infected patients, each of SARS-CoV, MERS-CoV, and SARS-CoV-2 has been
evolutionarily acquiring an ability to encode numerous proteins to impair type-1 interferon-…

[HTML][HTML] A critical analysis of SARS-CoV-2 (COVID-19) complexities, emerging variants, and therapeutic interventions and vaccination strategies

CX Li, S Noreen, LX Zhang, M Saeed, PF Wu… - Biomedicine & …, 2022 - Elsevier
Coronavirus is a family of viruses that can cause diseases such as the common cold, severe
acute respiratory syndrome (SARS), and Middle East respiratory syndrome (MERS). The …

[HTML][HTML] Origin, pathogenesis, diagnosis and treatment options for SARS-CoV-2: a review

H Sajjad, M Majeed, S Imtiaz, M Siddiqah, A Sajjad… - Biologia, 2021 - Springer
… Although in some acute phase numerous cycling T cells efficiently stop the SARS-COV-2
infection yet in many cases immune response is not able to stop infection. Microbiota …

[HTML][HTML] Development of SARS-CoV-2 vaccines: should we focus on mucosal immunity?

L Moreno-Fierros, I García-Silva… - Expert Opinion on …, 2020 - Taylor & Francis
… Therefore, numerous SARS-CoV vaccine candidates have been developed having as target
the full-length S protein. However, it should be considered that SARS-CoV is an RNA virus …

The emerging SARS-CoV-2 variants of concern

A Sanyaolu, C Okorie, A Marinkovic… - Therapeutic …, 2021 - journals.sagepub.com
… December of 2019, the coronavirus (SARS-CoV-2) has been … Organization to officially sanction
the SARS-CoV-2 outbreak as … intends to identify and report SARS-CoV-2 variants that are …

Existing antiviral options against SARS-CoV-2 replication in COVID-19 patients

R Ghanbari, A Teimoori, A Sadeghi… - Future …, 2020 - Taylor & Francis
… in numerous in vitro and in vivo studies as potential treatments against the SARS-CoV-2 […
antivirals that have potential efficacy against SARS-CoV-2 through targeting the structural …

[HTML][HTML] Exploring the future of SARS-CoV-2 treatment after the first two years of the pandemic: A comparative study of alternative therapeutics

BA Babalola, OS Akinsuyi, EO Folajimi, F Olujimi… - Biomedicine & …, 2023 - Elsevier
… The emergence of SARS-CoV-2 has led to a global pandemic, … a more effective means of
combating SARS-CoV-2, and future … fight against SARS-CoV-2 and its potential future variants. …

[HTML][HTML] Structural biology of SARS-CoV-2 and implications for therapeutic development

H Yang, Z Rao - Nature Reviews Microbiology, 2021 - nature.com
SARS-CoV-2 proteins can individually perform essential physiological roles, be … with
numerous host cellular factors. In this Review, we delineate the structural features of SARS-CoV-2 …

[HTML][HTML] Challenges and opportunities from targeting inflammatory responses to SARS-CoV-2 infection: a narrative review

V Lariccia, S Magi, T Serfilippi, M Toujani… - Journal of Clinical …, 2020 - mdpi.com
… of the severe acute respiratory syndrome related to coronavirus-2 (SARS-CoV-2). A major
… While drugs that target SARS-CoV-2 entry or replication are expected to confer the greatest …