… Study on the Efficacy and Safety of Four Antiviral Drugs for Hospitalized COVID-19 Patients: Nirmatrelvir/Ritonavir, Simnotrelvir/Ritonavir, Molnupiravir and Azvudine

X Yu, R Luo, G Xie, J Ji, J Wang, X Li… - Infection and Drug …, 2024 - Taylor & Francis
… This study indicated Simnotrelvir/Ritonavir and Nirmatrelvir/Ritonavir were more potent in
shortening the hospital stay of hospitalized patients with COVID-19 compared to Azvudine …

Nirmatrelvir and ritonavir combination against COVID‐19 caused by omicron BA. 2.2 in the elderly: A single‐center large observational study

C Chen, R Li, S Xing, L Cao, Y Qu, Q Lv… - Immunity …, 2024 - Wiley Online Library
… have been developed, among which nirmatrelvirritonavir is highly recommended. We
intended to assess the effectiveness and safety of nirmatrelvirritonavir in the elderly mild-to-…

Real-world use of nirmatrelvirritonavir in outpatients with COVID-19 during the era of omicron variants including BA. 4 and BA. 5 in Colorado, USA: a retrospective …

NR Aggarwal, KC Molina, LE Beaty… - The Lancet Infectious …, 2023 - thelancet.com
… Included patients had a positive SARS-CoV-2 test or nirmatrelvirritonavir … a
nirmatrelvirritonavir order. We propensity score matched patients treated with nirmatrelvirritonavir

The antiviral effect of nirmatrelvir/ritonavir during COVID-19 pandemic real-world data

V Petrakis, P Rafailidis, G Trypsianis, D Papazoglou… - Viruses, 2023 - mdpi.com
… the safety and efficacy of nirmatrelvir/ritonavir in preventing severe … , and the efficacy of
nirmatrelvir/ritonavir is evaluated in a … the impact of nirmatrelvir/ritonavir and determine strategy …

The impact of nirmatrelvir-ritonavir in reducing hospitalizations among high-risk patients with SARS-CoV-2 during the omicron predominant era

MM Al-Obaidi, AB Gungor, S Murugapandian… - The American Journal of …, 2023 - Elsevier
… Despite the reported benefits of nirmatrelvir-ritonavir, greater health care provider awareness
is required because many at-risk individuals are not being offered this important treatment …

Clinical effectiveness of nirmatrelvir plus ritonavir in the treatment of COVID-19 for patients with dementia

TH Liu, WH Hsu, YW Tsai, JY Wu, PY Huang… - Journal of the American …, 2023 - jamda.com
… Information about the residential settings of patients, such as whether they resided in nursing
homes or other residential care settings, was not included in the dataset. Nonetheless, our …

Effectiveness, tolerability and prescribing choice of antiviral molecules molnupiravir, remdesivir and nirmatrelvir/r: a real-world comparison in the first ten months of use

C Del Borgo, S Garattini, C Bortignon, A Carraro… - Viruses, 2023 - mdpi.com
… ), blocking the viral assembly; ritonavir acts as a pharmacologic booster of nirmatrelvir,
inhibiting the CYP3A4 enzyme in order to maintain high plasmatic levels of nirmatrelvir itself [7]. …

SARS-CoV-2 virologic rebound with nirmatrelvirritonavir therapy: an observational study

GE Edelstein, J Boucau, R Uddin, C Marino… - Annals of Internal …, 2023 - acpjournals.org
… patients treated with nirmatrelvirritonavir than in untreated patients is currently a question
of clinical interest. This observational study in a multicenter health care system compared the …

Real-world effectiveness of molnupiravir, nirmatrelvir-ritonavir, and sotrovimab on preventing hospital admission among higher-risk patients with COVID-19 in Wales …

A Evans, C Qi, JO Adebayo, J Underwood, J Coulson… - Journal of Infection, 2023 - Elsevier
… In this retrospective cohort study, we sought to compare the effectiveness of sotrovimab,
molnupiravir, and nirmatrelvir-ritonavir in preventing hospital admission and death in higher-risk …

Real-world effectiveness of nirmatrelvir/ritonavir use for COVID-19: A population-based cohort study in Ontario, Canada

KL Schwartz, J Wang, M Tadrous, BJ Langford… - medRxiv, 2022 - medrxiv.org
… world effectiveness of nirmatrelvir/ritonavir to prevent severe … We compared nirmatrelvir/ritonavir
treated patients to … days was lower in the nirmatrelvir/ritonavir treated group compared to …