C Chen, R Li, S Xing, L Cao, Y Qu, Q Lv… - Immunity …, 2024 - Wiley Online Library
… have been developed, among which nirmatrelvir–ritonavir is highly recommended. We intended to assess the effectiveness and safety of nirmatrelvir–ritonavir in the elderly mild-to-…
NR Aggarwal, KC Molina, LE Beaty… - The Lancet Infectious …, 2023 - thelancet.com
… Included patients had a positive SARS-CoV-2 test or nirmatrelvir–ritonavir … a nirmatrelvir–ritonavir order. We propensity score matched patients treated with nirmatrelvir–ritonavir …
… the safety and efficacy of nirmatrelvir/ritonavir in preventing severe … , and the efficacy of nirmatrelvir/ritonavir is evaluated in a … the impact of nirmatrelvir/ritonavir and determine strategy …
MM Al-Obaidi, AB Gungor, S Murugapandian… - The American Journal of …, 2023 - Elsevier
… Despite the reported benefits of nirmatrelvir-ritonavir, greater health care provider awareness is required because many at-risk individuals are not being offered this important treatment …
… Information about the residential settings of patients, such as whether they resided in nursing homes or other residential care settings, was not included in the dataset. Nonetheless, our …
C Del Borgo, S Garattini, C Bortignon, A Carraro… - Viruses, 2023 - mdpi.com
… ), blocking the viral assembly; ritonavir acts as a pharmacologic booster of nirmatrelvir, inhibiting the CYP3A4 enzyme in order to maintain high plasmatic levels of nirmatrelvir itself [7]. …
GE Edelstein, J Boucau, R Uddin, C Marino… - Annals of Internal …, 2023 - acpjournals.org
… patients treated with nirmatrelvir–ritonavir than in untreated patients is currently a question of clinical interest. This observational study in a multicenter health care system compared the …
A Evans, C Qi, JO Adebayo, J Underwood, J Coulson… - Journal of Infection, 2023 - Elsevier
… In this retrospective cohort study, we sought to compare the effectiveness of sotrovimab, molnupiravir, and nirmatrelvir-ritonavir in preventing hospital admission and death in higher-risk …
… world effectiveness of nirmatrelvir/ritonavir to prevent severe … We compared nirmatrelvir/ritonavir treated patients to … days was lower in the nirmatrelvir/ritonavir treated group compared to …