Nirmatrelvir-ritonavir and COVID-19 mortality and hospitalization among patients with vulnerability to COVID-19 complications

CR Dormuth, JD Kim, A Fisher, J Piszczek… - JAMA network …, 2023 - jamanetwork.com
Nirmatrelvir and ritonavir was approved based on interim efficacy and safety data from the …
nirmatrelvir and ritonavir or placebo within 5 days of symptom onset. Nirmatrelvir and ritonavir

The effect of nirmatrelvirritonavir on the long‐term risk of neuropsychiatric sequelae following COVID‐19

TH Liu, JY Wu, PY Huang, YW Tsai… - Journal of Medical …, 2023 - Wiley Online Library
… The retrospective cohort was conducted to assess the effect of nirmatrelvir-ritonavir (NMV-r)
on the long-term risk of neuropsychiatric sequela following COVID-19. TriNetX research …

[HTML][HTML] Association of Molnupiravir and Nirmatrelvir-Ritonavir with preventable mortality, hospital admissions and related avoidable healthcare system cost among …

AKC Wai, CY Chan, AWL Cheung, K Wang… - The Lancet Regional …, 2023 - thelancet.com
… of Molnupiravir and Nirmatrelvir-ritonavir use in reducing mortality in this population. …
Among these patients, 55.4% were male, almost 40% were from care homes, and 5.1% of these …

[HTML][HTML] Nirmatrelvir plus ritonavir in COVID-19: a profile of its use

HA Blair - Drugs & Therapy Perspectives, 2023 - Springer
ritonavir slows the breakdown of nirmatrelvir to increase its therapeutic benefit. Nirmatrelvir
plus ritonavir … increased nirmatrelvir exposure; therefore, nirmatrelvir plus ritonavir can be …

[HTML][HTML] Can nirmatrelvir/ritonavir treatment shorten the duration of COVID-19 isolation?

H Kim, JS Yang, JH Ko, M Lee, JY Lee, S Park… - Frontiers in …, 2022 - frontiersin.org
… patients for each of the nirmatrelvir/ritonavir and supportive care groups. In the
nirmatrelvir/ritonavir group, 300 mg nirmatrelvir with 100 mg ritonavir was administered orally every …

[HTML][HTML] Efficacy and safety of nirmatrelvir/ritonavir, molnupiravir, and remdesivir in a real-world cohort of outpatients with COVID-19 at high risk of progression: the …

G Tiseo, C Barbieri, V Galfo, S Occhineri… - Infectious Diseases and …, 2023 - Springer
… We found that almost half of patients treated with nirmatrelvir/ritonavir developed an AE,
mainly represented by dysgeusia. Although AEs were usually mild, dysgeusia and …

Availability of oral antivirals against SARS-CoV-2 infection and the requirement for an ethical prescribing approach

R Dal-Ré, SL Becker, E Bottieau… - The Lancet Infectious …, 2022 - thelancet.com
… should be given in health-care facilities with trained staff to manage … , molnupiravir and
nirmatrelvirritonavir will primarily be … care centres, hospital pharmacies (or similar health-care

COVID-19 hospitalization risk after outpatient nirmatrelvir/ritonavir use, January to August 2022, North Carolina

HI Henderson, DA Wohl, WA Fischer… - Journal of …, 2024 - academic.oup.com
… of nirmatrelvir/ritonavir therapy with time to hospitalization by estimating adjusted HRs and
assessed the impact of nirmatrelvir/ritonavir on … regarding long-term care facility residence, we …

[HTML][HTML] Nirmatrelvir/ritonavir utilization for the treatment of non-hospitalized adults with COVID-19 in the National Veterans Affairs (VA) Healthcare System

HJ Appaneal, KL LaPlante, VV Lopes, C Martin… - Infectious Diseases and …, 2024 - Springer
… Indeed, recent reports have shown that nirmatrelvir/ritonavir use in the nursing home
setting (where frail patients are often concentrated) has been suboptimal [33]. Interventions to …

Real-world use of nirmatrelvirritonavir: who benefits?

KC Molina, AA Ginde - The Lancet Infectious Diseases, 2023 - thelancet.com
… of nirmatrelvirritonavir supports the … nirmatrelvirritonavir was dispensed had
symptoms for more than 5 days or were asymptomatic—populations in which nirmatrelvirritonavir