Cost-effectiveness of oral nirmatrelvir/ritonavir in patients at high risk for progression to severe COVID-19 in the United States

J Carlson, V Foos, A Kasle, T Mugwagwa, F Draica… - Value in Health, 2024 - Elsevier
… SARS-CoV-2 protease inhibitor antiviral consisting of nirmatrelvir and ritonavir (NMV/r) as an
… Estimate from 3 days of long-term care at skilled nursing facility using cost from ICER 2022 …

Comparison of Azvudine and Nirmatrelvir/Ritonavir and Combined Use in Patients with COVID-19

CY Hu, WS Cui, Y Lei, YW Tang, YY Zhang… - Infection and Drug …, 2023 - Taylor & Francis
… group, 114 were treated with nirmatrelvir/ritonavir and assigned to the nirmatrelvir/ritonavir
group, and 41 were treated with both azvudine and nirmatrelvir/ritonavir. A flowchart of the …

Nirmatrelvir/Ritonavir and Molnupiravir: an update on COVID-19 Antivirals in the Omicron era

F Faraz, MEU Rehman, A Shahid… - Expert Review of …, 2023 - Taylor & Francis
… One of the biggest challenges is that Pfizer did not grant access to nirmatrelvir/ritonavir for
… that nirmatrelvir and ritonavir are both metabolized by the CYP3A4 enzyme, and ritonavir is …

Nirmatrelvir/ritonavir and remdesivir against symptomatic treatment in high-risk COVID-19 outpatients to prevent hospitalization or death during the Omicron era: a …

S Rajme-López, BA Martinez-Guerra… - Therapeutic …, 2024 - journals.sagepub.com
… remdesivir, and 332 received nirmatrelvir/ritonavir. The median age … The use of
nirmatrelvir/ritonavir was associated with an … hospitalization or death [nirmatrelvir/ritonavir odds …

Real‐world effectiveness of Azvudine versus nirmatrelvirritonavir in hospitalized patients with COVID‐19: A retrospective cohort study

G Deng, D Li, Y Sun, L Jin, Q Zhou… - Journal of medical …, 2023 - Wiley Online Library
… of Azvudine versus nirmatrelvirritonavir treatments in real-… recipients and 281
nirmatrelvirritonavir recipients who did not … -19 patients compared with nirmatrelvirritonavir in …

Effectiveness of COVID-19 treatment with nirmatrelvirritonavir or molnupiravir among US veterans: target trial emulation studies with one-month and six-month …

KL Bajema, K Berry, E Streja, N Rajeevan… - Annals of internal …, 2023 - acpjournals.org
nirmatrelvirritonavir, but there is less evidence of benefit for molnupiravir (3–5). Effectiveness
studies of nirmatrelvirritonavir … Early observational studies of nirmatrelvirritonavir (6–9) …

Real-world effectiveness of nirmatrelvir-ritonavir versus azvudine in hospitalized patients with COVID-19 during the omicron wave in Beijing: a multicenter …

X Han, D Gao, C Li, X Yuan, J Cui, W Zhao, F Xie… - BMC Infectious …, 2024 - Springer
… on 28 days were observed between patients receiving nirmatrelvir-ritonavir and azvudine.
However, it is worth noticing that nirmatrelvir-ritonavir appears to hold an advantage over …

[HTML][HTML] Paxlovid (Nirmatrelvir/Ritonavir): A new approach to Covid-19 therapy?

SMR Hashemian, A Sheida, M Taghizadieh… - Biomedicine & …, 2023 - Elsevier
… inhibitor, ritonavir, to create Paxlovid (Nirmatrelvir/Ritonavir). … is inhibited by ritonavir to
lengthen the half-life of nirmatrelvir, … the current literature on nirmatrelvir and ritonavir efficacy in …

Efficacy of nirmatrelvir and ritonavir for post‐acute COVID‐19 sequelae beyond 3 months of SARS‐CoV‐2 infection

MH Chuang, JY Wu, TH Liu, WH Hsu… - Journal of Medical …, 2023 - Wiley Online Library
… demonstrated the benefit of the novel antiviral agent nirmatrelvir plus ritonavir (NMV-r) in
reducing the risk of severe COVID-19. Furthermore, many real-world studies have …

[PDF][PDF] Evidence-based recommendations on the use of nirmatrelvir/ritonavir (Paxlovid) for adults in Ontario

AS Komorowski, A Tseng… - Science briefs of …, 2022 - covid19-sciencetable.ca
nirmatrelvir/ritonavir or placebo. The trial showed that in patients with COVID-19 who were
well enough to be cared for at home, nirmatrelvir/ ritonavircare unit of a nursing home for …