Coronavirus disease 2019 rebounds following nirmatrelvir/ritonavir treatment

CC Lai, PR Hsueh - Journal of Medical Virology, 2023 - Wiley Online Library
… Therefore, concerns about the recurrence of symptoms should not be a reason to avoid
using ritonavir-boosted nirmatrelvir. Although insufficient drug exposure by individual …

Describing COVID-19 Patients During The First Two Months of Paxlovid (Nirmatrelvir/Ritonavir) Initiation in a Large HMO in Israel

L Tene, G Chodick, N Fallach, W Ansari… - medRxiv, 2022 - medrxiv.org
… (nirmatrelvir/ritonavir) on patient outcomes and healthcare resource utilization (HCRU). We
also intend to assess the comparability of the patients who were treated with Paxlovid versus …

[HTML][HTML] The effect of nirmatrelvir plus ritonavir on the long-term risk of epilepsy and seizure following COVID-19: A retrospective cohort study including 91,528 patients

TH Liu, JY Wu, PY Huang, YW Tsai… - The Journal of …, 2023 - ncbi.nlm.nih.gov
… We read with interest the recent meta-analysis assessing the clinical efficacy and safety of
nirmatrelvir plus ritonavir (NMV-r) in the treatment of patients with COVID-19. Based on the …

Clinical effectiveness of nirmatrelvir plus ritonavir in patients with COVID‐19 and substance use disorders based on real‐world data

TH Liu, PY Huang, JY Wu, MH Chuang… - Journal of Medical …, 2023 - Wiley Online Library
… This study assessed the clinical efficacy of nirmatrelvir plus ritonavir (NMV-r) in treating
patients with coronavirus disease-2019 (COVID-19) and substance use disorders (SUDs). This …

Oral nirmatrelvir and ritonavir in nonhospitalized vaccinated patients with coronavirus disease 2019

S Ganatra, SS Dani, J Ahmad, A Kumar… - Clinical Infectious …, 2023 - academic.oup.com
… Treatment of coronavirus disease 2019 (COVID-19) with nirmatrelvir plus ritonavir (NMV-r)
in high-risk nonhospitalized unvaccinated patients reduced the risk of progression to severe …

Comparable outcomes for bebtelovimab and ritonavir-boosted nirmatrelvir treatment in high-risk patients with coronavirus disease-2019 during severe acute …

RR Razonable, JC O'Horo, SN Hanson… - The Journal of …, 2022 - academic.oup.com
… therapy for patients unable to receive intravenous remdesivir or oral nirmatrelvir-ritonavir [1]. …
We compare their outcomes with those in patients treated with ritonavir-boosted nirmatrelvir, …

Population-level strategies for nirmatrelvir/ritonavir prescribing—a cost-effectiveness analysis

A Savinkina, AD Paltiel, JS Ross… - Open Forum Infectious …, 2022 - academic.oup.com
… In addition to the baseline policy of treating nobody with nirmatrelvir/ritonavir, we
considered 4 increasingly expansive eligibility policies for persons with confirmed SARS-CoV-2 …

Pharmacokinetics of oral nirmatrelvir/ritonavir, a protease inhibitor for treatment of COVID‐19, in subjects with renal impairment

SS Toussi, JM Neutel, J Navarro… - Clinical …, 2022 - Wiley Online Library
nirmatrelvir and ritonavir in human plasma and nirmatrelvir in human urine were validated
at York Bioanalytical Solutions (York, UK). The calibration curve range for the plasma method …

[HTML][HTML] Current status of oral antiviral drug treatments for SARS-CoV-2 infection in non-hospitalized patients

DV Parums - … science monitor: international medical journal of …, 2022 - ncbi.nlm.nih.gov
… A recent success in the latter group is nirmatrelvir/ritonavir (… inhibitor, PF-07321332;
nirmatrelvir/ritonavir (Paxlovid ® ) in … ) for the oral antiviral drug, nirmatrelvir/ritonavir (Paxlovid ® ), …

Remdesivir or Nirmatrelvir/Ritonavir Therapy for Omicron SARS-CoV-2 Infection in Hematological Patients and Cell Therapy Recipients

JL Piñana, I Heras, TF Aiello, I García-Cadenas… - Viruses, 2023 - mdpi.com
… this current study received concomitant treatment with remdesivir plus nirmatrelvir/ritonavir. …
or nirmatrelvir/ritonavir during the Omicron SARS-CoV-2 period. Nirmatrelvir/ritonavir was …