… Ritonavir-boosted nirmatrelvir (nirmatrelvir–ritonavir) and … In many settings, nirmatrelvir–ritonavir
has been the most … death through day 28 with nirmatrelvir–ritonavir, but there has been …

… Two oral antiviral agents, molnupiravir and nirmatrelvir/ritonavir, have … In the EPIC-HR study,
the nirmatrelvir/ritonavir group had a … of molnupiravir and nirmatrelvir/ritonavir in reducing …

… nirmatrelvir with or without 83.3 mg/kg ritonavir. In the absence of ritonavir, 250 mg/kg nirmatrelvir
… When combined with ritonavir, we noted nirmatrelvir plasma exposure exceeding that …

… ), blocking the viral assembly; ritonavir acts as a pharmacologic booster of nirmatrelvir,
inhibiting the CYP3A4 enzyme in order to maintain high plasmatic levels of nirmatrelvir itself [7]. …

… nirmatrelvir-ritonavir in addition to standard care, whereas those in the control group only
received standard care… 324 patients who were administered nirmatrelvir-ritonavir and an equal …

… Nirmatrelvir is used in combination with ritonavir to maintain the blood concentration of
nirmatrelvir at effective levels. Ritonavir has a potent inhibitory effect on drug metabolizing …

… of nirmatrelvir/ritonavir treatment in a … nirmatrelvir/ritonavir were compared to those
who did not. A logistic regression was run to determine factors associated with nirmatrelvir/ritonavir …

… Several randomized controlled trials and real-world cohort studies have demonstrated the
efficacies of nirmatrelvir plus ritonavir (NMV-r) and molnupiravir (MOV) in at-risk patients with …

… This study aimed to evaluate the cost-effectiveness of nirmatrelvir/ritonavir (Nir/Rit) for
adult outpatients with COVID-19 from the perspective of a Japanese public healthcare payer. …

… Nirmatrelvir/ritonavir is … nirmatrelvir/ritonavir affects the presence of SARS-CoV-2 in the
upper respiratory tract. The purpose of the current study is to determine if nirmatrelvir/ritonavir …