… This release of cytokines is followed by rapid development of lung tissue damage resulting
… investigate such combination therapy in older susceptible individuals with comorbidities who …

… In recent years, the issue of cytokine storms has attracted considerable critical attention, and
… The number of literature (n=1336, 55.5%) in the third stage exceeds all previous literature …

… in aged NHPs [67]. Similarly, in SARS-CoV-infected BALB/c mice, disease severity in aged
… produced elevated levels of pro-inflammatory cytokines such as TNF, IL-6, IL1-β, and iNOS. …

… A special case of MASH arises in patients with cytokine release syndrome (CRS), a
clinical syndrome accompanying novel immunotherapy treatment of B-precursor leukemia [14]. …

… in the cytokine storm by inducing the suppressor of cytokine … IL-6 is an essential target in
cytokine release syndrome (CRS) … that cytokine storm is affected by various criteria such as old …

… the release of a large amount of pro-inflammatory cytokines in an event known as “cytokine
storm.… Several studies analyzing cytokine profiles from COVID-19 patients suggested that the …

… Reduced counts and functional exhaustion of T lymphocytes, and cytokine release …
TH17 cells further supporting a TH17 type cytokine storm in this disease[12]. Cytokine storm …

… to a disease, also called cytokine release syndrome. I have … that a cytokine storm occurs
when cytokine release is severe. … the previous sections are one of the main causes of Cytokine …

… Severe patients were older; LDH, D-dimer and IL-6 were higher in severe group 44 … The
drug is currently approved for rheumatoid arthritis, giant cell arteritis and cytokine release …

… or cytokine release syndrome (44, 45). There were 2 additional COVID-19 patients who had
… We included hospitalized patients, aged 18 years or older, who were COVID-19 positive via …