… that human beings evolved on a diet with a ratio of omega-6 to omega-3 essential fatty
acids (EFA) of ~1 whereas in Western diets the ratio is 15/1 to 16.7/1. A high omega-6/omega-3 …

… Since this change in dietary omega–6/omega–3 ratio occurred within too short a time to …
capable of converting omega–6 to omega–3 fatty acids. As a result, a high omega–6/omega–3 …

… Some scientists have advocated diets with low ratios of omega-6 to omega-3 PUFAs for
the reasons discussed earlier in this article. Although it is true that a higher intake of EPA and …

Background: The consumption of omega-3 (n–3) and omega-6 (n–6) essential fatty acids in
Western diets is thought to have changed markedly during the 20th century. Objective: We …

… Several sources of information suggest that humans evolved on a diet with an equal ratio
of omega-6 (ω-6) to omega-3 (ω-3) fatty acids, whereas in today’s Western diet, this ratio is ~10:…

… -analysis to date examining the relations between omega-6 fatty acid (essentially LA) intake
… (ALA, the plant omega-3 fatty acid found primarily in soybean oil, of which 6% of fatty acids …

… recommend higher intake of omega-6 polyunsaturated fatty acids (n-6 PUFA) to reduce the
risk … However, the influence and potential dose–response relationship of n-6 PUFA on health …

… g of omega-3 fatty acids. From the available research, we are aware of no evidence of human
health problems associated with Alaskan Native consumption of high amounts of omega-3 …

… study highlight that the omega-6 fatty acid ARA appears increased, and omega-3 EPA and …
, and that increments in omega-3 LC-PUFAs consumption and an omega-6/omega-3 ratio of 2…

… of evidence relating intake of omega-3 and omega-6 PUFAs to cardiometabolic diseases.
We then address how PUFA metabolism is linked to Δ-5 and Δ-6 desaturases, and review the …