mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant

H Gruell, K Vanshylla, P Tober-Lau, D Hillus… - Nature medicine, 2022 - nature.com
… of serum neutralizing activity against Omicron. This study demonstrates that booster
immunizations can critically improve the humoral immune response against the Omicron variant. …

Current evidence on efficacy of COVID‐19 booster dose vaccination against the Omicron variant: A systematic review

S Chenchula, P Karunakaran… - Journal of medical …, 2022 - Wiley Online Library
… , and found that individuals who had received a booster dose with mRNA vaccines had shown
a potent neutralization antibodies against Omicron variant and only 4- to 6-fold lower than …

Effect of mRNA vaccine boosters against SARS-CoV-2 Omicron infection in Qatar

LJ Abu-Raddad, H Chemaitelly… - … England Journal of …, 2022 - Mass Medical Soc
… The messenger RNA (mRNA) boosters were highly effective against symptomatic delta …
against symptomatic omicron infection. However, with both variants, mRNA boosters led to strong …

mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant

WF Garcia-Beltran, KJS Denis, A Hoelzemer, EC Lam… - Cell, 2022 - cell.com
Omicron variant mutations used in this study were based on the most prevalent mutations
(>85% frequency) found in GISAID and reflect the dominant Omicron variant. The regions …

mRNA booster vaccination enhances antibody responses against SARS-CoV2 Omicron variant in individuals primed with mRNA or inactivated virus vaccines

B Zhang, J Huo, Y Huang, SY Teo, K Duan, Y Li… - Vaccines, 2022 - mdpi.com
mRNA vaccine (BNT162b2 or mRNA-1273) booster enhances humoral responses
against the Omicron variant in individuals vaccinated with either two prior doses of mRNA or …

[HTML][HTML] Breakthrough infections with SARS-CoV-2 omicron despite mRNA vaccine booster dose

C Kuhlmann, CK Mayer, M Claassen, T Maponga… - The Lancet, 2022 - thelancet.com
… supporting calls for booster doses while the omicron variant appears to be spreading
globally. Our study, however, demonstrates insufficient prevention of symptomatic infection in …

Omicron-specific mRNA vaccination alone and as a heterologous booster against SARS-CoV-2

Z Fang, L Peng, R Filler, K Suzuki, A McNamara… - Nature …, 2022 - nature.com
… immune elicitation against Omicron variant, we performed the following vaccination and
testing schedule. Two doses of 10 µg Omicron LNP-mRNA, as prime and boost two weeks apart …

[HTML][HTML] SARS-CoV-2 Omicron neutralization by therapeutic antibodies, convalescent sera, and post-mRNA vaccine booster

S Lusvarghi, SD Pollett, SN Neerukonda, W Wang… - BioRxiv, 2021 - ncbi.nlm.nih.gov
… Three immunizations of the Pfizer/BNT162b2 mRNAOmicron variant compared to two-vaccinations.
The emergence of the Omicron variant coincided with recommendations for booster

[HTML][HTML] Booster of mRNA-1273 vaccine reduces SARS-CoV-2 Omicron escape from neutralizing antibodies

NA Doria-Rose, X Shen, SD Schmidt, S O'Dell… - MedRxiv, 2021 - medrxiv.org
… A post-boost improvement in neutralization also was seen for Beta (3.4- and 2.6-fold less …
Thus, the boost provided improvement in neutralization of both the Omicron and Beta variants. …

Effectiveness of mRNA booster vaccination against mild, moderate, and severe COVID-19 caused by the Omicron variant in a large, population-based, Norwegian …

I Laake, SN Skodvin, K Blix… - The Journal of …, 2022 - academic.oup.com
Omicron infection. In a recent surveillance report from the United Kingdom, VE estimates for
mRNA booster vaccination against Omicron … 2–4 after the booster, declining to almost no …