Omics technologies for profiling toxin diversity and evolution in snake venom: impacts on the discovery of therapeutic and diagnostic agents

CM Modahl, RK Brahma, CY Koh… - Annual Review of …, 2020 - annualreviews.org
omics technologies can help to identify and characterize. Venom profiling with omics
technologies… rate, especially in regard to overall snake venom compositional characterization (4, …

Guiding recombinant antivenom development by omics technologies

AH Laustsen - New biotechnology, 2018 - Elsevier
… individual venom toxins. Focus is thus also directed towards the different omics technologies
… animal toxins have not so far been reported outside the field of snake venoms. However, for …

[HTML][HTML] Modern trends in animal venom research-omics and nanomaterials

YN Utkin - World journal of biological chemistry, 2017 - ncbi.nlm.nih.gov
… investigation of the venom proteome of the rear-fanged snake … classical snake venom
metalloproteinases found in all snake … The data discussed above indicate that omics technologies

Unraveling snake venom complexity with 'omics' approaches: challenges and perspectives

A Zelanis, AK Tashima - Toxicon, 2014 - Elsevier
… On the last decade or so, ‘omics’ methodologies have started being systematically used in …
complexity of snake venoms, both in terms of the assortment of toxins present in the venom of …

Snake venomics: fundamentals, recent updates, and a look to the next decade

CH Tan - Toxins, 2022 - mdpi.com
… Regardless of the debatable venom origin, snake venom aptly illustrates the composition …
advent of OMICS technology has completely revolutionized the study of venom composition. …

Colubrid venom composition: an-omics perspective

ILM Junqueira-de-Azevedo, PF Campos, ATC Ching… - Toxins, 2016 - mdpi.com
… Here we review the state of knowledge concerning rear-fanged snake venom composition,
emphasizing those toxins for which protein or transcript sequences are available. We have …

Omics meets biology: application to the design and preclinical assessment of antivenoms

JJ Calvete, L Sanz, D Pla, B Lomonte, JM Gutiérrez - Toxins, 2014 - mdpi.com
… neutralize the most relevant toxic activities of the snake venoms for which it was designed is
a … However, the study of the biochemical and toxicological complexity of snake venoms has …

Modern venomics—Current insights, novel methods, and future perspectives in biological and applied animal venom research

BM von Reumont, G Anderluh, A Antunes… - …, 2022 - academic.oup.com
… and toxin genes evolve based on modern “omics” methods. Translational research exploits
… molecule in snake venom. It has been considered that this is the case in all venoms because …

Venomics: integrative venom proteomics and beyond

JJ Calvete - Biochemical Journal, 2017 - portlandpress.com
… natural history of venoms, particularly those of snakes, which … The application of omics
technologies and other disciplines … snake venoms to their present-day variability landscape. …

Identification of Daboia siamensis venome using integrated multi-omics data

T Saethang, P Somparn, S Payungporn, S Sriswasdi… - Scientific reports, 2022 - nature.com
Snake venom compositions vary among different snake … a multi-omics approach to identify
venom composition of Daboia … All novelties found from analyses of our initiated snake omics