Optical biosensors for virus detection: prospects for SARS‐CoV‐2/COVID‐19

H Maddali, CE Miles, J Kohn, DM O'Carroll - ChemBioChem, 2021 - Wiley Online Library
… Advanced therapeutic studies have been carried out for targeting the spike protein in SARS-…
Designing and fabricating optical biosensors based on the receptors of SARS-CoV-2 could …

… of the SARS-CoV-2 spike protein across the blood–brain barrier, as revealed by a combination of a human cell culture model system and optical biosensing

D Petrovszki, FR Walter, JP Vigh, A Kocsis, S Valkai… - Biomedicines, 2022 - mdpi.com
… investigated by an optical biosensing method. We found that spike protein crossed the human
brain endothelial cell barrier effectively. Additionally, spike protein passage was found in a …

Monitoring serum spike protein with disposable photonic biosensors following SARS-CoV-2 vaccination

JS Cognetti, BL Miller - Sensors, 2021 - mdpi.com
… confirming the presence of SARS-CoV-2 spike protein in the serum of recently vaccinated
subjects, … A maximum concentration in SARS-CoV-2 spike protein was detected one day after …

Recent advances of representative optical biosensors for rapid and sensitive diagnostics of SARS-CoV-2

M Xu, Y Li, C Lin, Y Peng, S Zhao, X Yang, Y Yang - Biosensors, 2022 - mdpi.com
… on optical biosensors in SARS-CoV-2 diagnosis, including fluorescence biosensors, colorimetric
biosensors… with a limit of detection of 37 nM for the SARS-CoV-2 spike protein. Although …

Optical biosensors for diagnosis of COVID-19: nanomaterial-enabled particle strategies for post pandemic era

YS Tekin, SM Kul, O Sagdic, N Rodthongkum, B Geiss… - Microchimica Acta, 2024 - Springer
… demonstrated an LOD of 1.06 fg/mL SARS-CoV-2 spike protein in the linear detection range
from 2 to 32 fg/mL in 5 min. The recovery rate was found to be 80–120% in saliva samples. …

Rapid optical biosensing of SARS-CoV-2 spike proteins in artificial samples

Y Tao, S Bian, P Wang, H Zhang, W Bi, P Zhu… - Sensors, 2022 - mdpi.com
… In this study, the FO-BLI biosensor was developed to detect SARS-CoV-2 spike proteins in
artificial serum and saliva. The sandwich-based FO-BLI showed the capacity to detect ECD …

Applications of Electrochemical and Optical Biosensing Techniques Based on Nanomaterials for Detection of SARS-COV-2 Specific Antibodies: An Update Review

S Abdalkareem Jasim, T Mahmudiono… - Analytical and …, 2022 - abechem.com
… [40] have fabricated an ACEA biosensor based on RBD of SARS-CoV-2 spike protein and
have been able for discovering the anti-SARS-CoV-2 Abs by EIS technique with 0.1 μg/ml, 1.0 …

Optical detection of CoV-SARS-2 viral proteins to sub-picomolar concentrations

T Stanborough, FM Given, B Koch, CR Sheen… - ACS …, 2021 - ACS Publications
optical techniques for quantifying the binding of recombinant SARS-CoV-2 spike protein to
… To the best of our understanding, the SPR biosensor is not a conventional SPR assay, ie …

Optical biosensors for diagnostics of infectious viral disease: A recent update

A Sharma, RK Mishra, KY Goud, MA Mohamed… - Diagnostics, 2021 - mdpi.com
… was developed to detect antibodies against SARS-CoV-2 spike protein [48]. The sensing
mechanism relies on the localized surface plasmon resonance (LSPR) involving gold …

SARS-CoV-2 spike protein detection through a plasmonic D-shaped plastic optical fiber aptasensor

N Cennamo, L Pasquardini, F Arcadio, L Lunelli… - Talanta, 2021 - Elsevier
… SARS-CoV-2 spike protein binding was optically measured without any amplification
systems. Moreover, the specificity of the biosensor system was tested using both non-sense …