[HTML][HTML] Oral antivirals for the prevention and treatment of SARS-CoV-2 infection

V Soriano, C De-Mendoza, B Edagwa, A Treviño… - AIDS …, 2022 - ncbi.nlm.nih.gov
… that oral small molecule antivirals that halt SARS-CoV-2 … administration is required, oral
antivirals offer treatments in an … The advent of additional oral antivirals, the assessment of …

[HTML][HTML] First-generation oral antivirals against SARS-CoV-2

P Sendi, RR Razonable, SB Nelson, A Soriano… - Clinical Microbiology …, 2022 - Elsevier
… of oral drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by …
of the first-generation oral antiviral agents against SARS-CoV-2. Parenteral therapeutics, …

Availability of oral antivirals against SARS-CoV-2 infection and the requirement for an ethical prescribing approach

R Dal-Ré, SL Becker, E Bottieau… - The Lancet Infectious …, 2022 - thelancet.com
The first two oral antivirals, molnupiravir and nirmatrelvir–ritonavir, are now becoming available
in many countries. These medicines will be indicated to treat mild-to-moderate COVID-…

[HTML][HTML] Current status of oral antiviral drug treatments for SARS-CoV-2 infection in non-hospitalized patients

DV Parums - … science monitor: international medical journal of …, 2022 - ncbi.nlm.nih.gov
… rates, outbreaks of new SARS-CoV-2 variants, incomplete … oral antiviral drugs that can
treat SARS-CoV-2 infection at an early stage. On 4 th November 2021, the first oral antiviral for …

An oral SARS-CoV-2 Mpro inhibitor clinical candidate for the treatment of COVID-19

DR Owen, CMN Allerton, AS Anderson… - Science, 2021 - science.org
orally bioavailable SARS-CoV-2 main protease inhibitor with in vitro pan-human coronavirus
antiviral … the in vitro cellular antiviral activity of PF-07321332 against SARS-CoV-1, MERS-…

Oral disease-modifying antirheumatic drugs and immunosuppressants with antiviral potential, including SARS-CoV-2 infection: a review

YC Tsai, TF Tsai - Therapeutic Advances in Musculoskeletal …, 2020 - journals.sagepub.com
SARS-CoV-2 in part I, and antiviral mechanisms plus trial evidence for viruses other than
SARS-CoV-2 … CQ and HCQ are reported to have strong antiviral property for SARS-CoV in vitro. …

Human safety, tolerability, and pharmacokinetics of molnupiravir, a novel broad-spectrum oral antiviral agent with activity against SARS-CoV-2

WP Painter, W Holman, JA Bush… - Antimicrobial agents …, 2021 - Am Soc Microbiol
… activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in
human … coronavirus (SARS-CoV) or Middle East respiratory syndrome coronavirus (MERS-CoV) …

4′-Fluorouridine is an oral antiviral that blocks respiratory syncytial virus and SARS-CoV-2 replication

J Sourimant, CM Lieber, M Aggarwal, RM Cox, JD Wolf… - Science, 2022 - science.org
… RSV and SARS-CoV-2 revealed transcriptional stalling after incorporation. Once-daily oral
… or 20 mg/kg in ferrets infected with different SARS-CoV-2 variants of concern, initiated 24 or …

[HTML][HTML] SARS-CoV-2 rebound with and without use of COVID-19 oral antivirals

DJ Smith - MMWR. Morbidity and Mortality Weekly Report, 2023 - cdc.gov
antiviral therapies are widely available, they are underutilized, possibly because of reports
of SARS-CoV… To enhance current understanding of rebound, CDC reviewed SARS-CoV-2 …

Molnupiravir—a novel oral anti-SARS-CoV-2 agent

CC Lee, CC Hsieh, WC Ko - Antibiotics, 2021 - mdpi.com
… , severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has rapidly … oral antiviral
agents are urgently needed to treat coronavirus disease-2019 (COVID-19), block SARS-CoV-…