Oral SARS-CoV-2 inoculation establishes subclinical respiratory infection with virus shedding in golden Syrian hamsters

ACY Lee, AJ Zhang, JFW Chan, C Li, Z Fan, F Liu… - Cell Reports …, 2020 - cell.com
… % of the oral infections (10/12 hamsters) have a level of detectable viral shedding from oral
swabs … Our findings indicate that the oral acquisition of SARS-CoV-2 can establish subclinical …

Oral SARS-CoV-2 inoculation causes nasal viral infection leading to olfactory bulb infection: an experimental study

R Ueha, T Ito, R Furukawa, M Kitabatake… - Frontiers in cellular …, 2022 - frontiersin.org
SARS-CoV-2 may also spread to the nasal cavity via the oraloral infection can also transmit
the virus to the OM and OB. … first explored whether oral SARS-CoV-2 inoculation, not nasal …

Adenovirus type 5 SARS-CoV-2 vaccines delivered orally or intranasally reduced disease severity and transmission in a hamster model

SN Langel, S Johnson, CI Martinez… - Science Translational …, 2022 - science.org
… a postvaccination infection by inoculating vaccinated hamsters with SARS-CoV-2. Orally
or intranasally vaccinated hamsters had decreased viral RNA and infectious virus in the nose …

[HTML][HTML] Fecal-oral transmission of SARS-CoV-2: A systematic review of evidence from epidemiological and experimental studies

MB Termansen, S Frische - American journal of infection control, 2023 - Elsevier
… if SARS-CoV-2 has a potential for fecal-oral transmission by … fecal-oral transmission exists
and if fecally shed SARS-CoV-2 is … Further, we found 23 studies experimentally inoculating

Oral and intranasal Ad5 SARS-CoV-2 vaccines decrease disease and viral transmission in a golden hamster model

SN Langel, S Johnson, CI Martinez, SN Tedjakusuma… - BioRxiv, 2021 - biorxiv.org
… During vaccination but prior to SARS-CoV-2 inoculation, all animals were gaining weight
at a similar rate (Extended data Fig. 1). After SARS-CoV-2 inoculation, we observed …

CPC-containing oral rinses inactivate SARS-CoV-2 variants and are active in the presence of human saliva

ER Anderson, EI Patterson… - Journal of medical …, 2022 - microbiologyresearch.org
2 (ACE-2) receptor in oral gingival epithelia and salivary glands and the infection of these
tissues by SARS-CoV-2 … as compared to the water control after incubation with inoculum for 5 …

[HTML][HTML] Low-dose and oral exposure to SARS-CoV-2 may help us understand and prevent severe COVID-19

WP Hausdorff, J Flores - International Journal of Infectious Diseases, 2021 - Elsevier
… Could oral ingestion, and/or low exposure doses, account at least partly for the wide … model,
oral inoculation with what would be a high intranasal dose of SARS-CoV-2 could establish a …

Potential intestinal infection and faecal–oral transmission of SARS-CoV-2

M Guo, W Tao, RA Flavell, S Zhu - Nature reviews Gastroenterology & …, 2021 - nature.com
… Upon intranasal inoculation of SARS-CoV-2 to seven Rhesus macaques at 10 6 TCID50,
viral RNA-positive anal swabs were observed at 3 dpi in all infected monkeys, followed by a …

Oral bacteria combined with an intranasal vaccine protect from influenza A virus and SARS-CoV-2 infection

M Nagai, M Moriyama, T Ichinohe - MBio, 2021 - Am Soc Microbiol
… Aliquots of 100 μl of serial 10-fold dilutions of the oral and nasal washes were inoculated
into brain heart infusion agar plates (BD 252109). After incubation at 37C overnight under the …

SARS-CoV-2 Infection in the Gastrointestinal Tract: Fecal–Oral Route of Transmission for COVID-19?

XJ Meng, TJ Liang - Gastroenterology, 2021 - gastrojournal.org
SARS-CoV-2 are the common link in both respiratory and GI tracts, regardless of the route of
infection. In animals intranasally inoculated with SARS-CoV-2, … released from SARS-CoV-2–…