… of pyroptosis in sepsis and SAOD. As our understanding of the functions of pyroptosis improves,
… associated with pyroptosis to improve clinical outcomes appears promising in the future. …

… to be involved in septic multiple organ function damage. This review provides an overview
of how pyroptosis played an important role in sepsis and sepsis induced organ dysfunction. …

… bacterial infection because appropriate pyroptosis can minimize tissue damage. Even so, …
Therefore, NLRP 3 may be a promising target for sepsis-induced multiple organ dysfunction…

… causing organ failure or septic shock (7–10). This review primarily focuses on the progress
of potential therapeutic targets for pyroptosis in sepsis. The Development of Pyroptosis …

… on the prognosis of septic shock [16, 17]. Organ damage caused by overactivated pyroptosis
has been demonstrated … It is important to eliminate the adverse effect of pyroptosis in sepsis. …

… Combined with the pathogenesis of sepsis, it is not difficult to find that pyroptosis plays a key
… is an important cause of multiple organ dysfunction syndromes and septic shock [2]. Anyone …

… is defined as a dysregulated host response to infection, resulting in life-threatening organ
dysfunction including physiologic, pathologic, and biochemical abnormalities (1) . Furthermore, …

… The research on neutrophil pyroptosis has attracted more and … pyroptosis in sepsis still
did not cause enough attention. As we all know, sepsis is a life-threatening organ dysfunction …

… , is the leading cause of pyroptotic endothelial dysfunctions in infection. Mechanisms of
organ failure and death in patients with sepsis are little known, and autopsy studies do not show …

… leading to tissue damage and organ dysfunction. Consequently, dysregulated pyroptotic
responses … The roles of gasdermin-mediated pyroptosis in various conditions like infection and …