The role of adjuvant immunomodulatory agents for treatment of severe influenza

DS Hui, N Lee, PK Chan, JH Beigel - Antiviral research, 2018 - Elsevier
drugs on the clinical outcome in severe influenza. This review provides an update on the
potential role of different immuno-modulatory agents and other … with severe influenza with a …

Treating influenza with statins and other immunomodulatory agents

DS Fedson - Antiviral Research, 2013 - Elsevier
… of treating influenza patients with statins and other immunomodulatory agents. I start with
an account of its genesis in the experience of statin treatment of patients with acute coronary …

The cytokine storm of severe influenza and development of immunomodulatory therapy

Q Liu, Y Zhou, Z Yang - Cellular & molecular immunology, 2016 - nature.com
… Several other immunomodulatory agents are being assessed for their efficacy, both in vitro
and in vivo. Lin and colleagues 58 have confirmed that CCR inhibitor-treated mice had a …

Adjunctive therapies and immunomodulating agents for severe influenza

DSC Hui, N Lee - Influenza and other Respiratory Viruses, 2013 - Wiley Online Library
… This article reviews the potential role of adjunctive therapies and immunomodulating
agents in the management of patients hospitalized with severe influenza and other acute

Adjunctive therapies and immunomodulatory agents in the management of severe influenza

DS Hui, N Lee, PK Chan - Antiviral research, 2013 - Elsevier
… More animal experiments and detailed human observational studies and (where feasible)
RCTs are needed to evaluate the efficacy of other agents with potential immunomodulatory

Passive immune therapy and other immunomodulatory agents for the treatment of severe influenza: systematic review and meta‐analysis

VW Lim, L Tudor Car, YS Leo… - Influenza and Other …, 2020 - Wiley Online Library
… guidelines do not recommend any immunomodulatory therapies as adjunctive treatments.3 …
on immunomodulatory agents other than corticosteroids for the treatment of severe influenza. …

Immunomodulatory therapy for severe influenza

I Darwish, S Mubareka, WC Liles - Expert review of anti-infective …, 2011 - Taylor & Francis
… -8, IL-10, IL-6, IFN-γ, TNF, MIP-1α and soluble IL-2, were elevated compared with other
influenza strains. … This review will focus on immunomodulatory agents for the treatment of severe

Confronting the next influenza pandemic with anti‐inflammatory and immunomodulatory agents: why they are needed and how they might work

DS Fedson - Influenza and other respiratory viruses, 2009 - Wiley Online Library
… and immunomodulatory agents along with an antiviral agent was … In other models of acute
lung injury, COX-2 inhibition actually … Another report has compared survival rates of mice …

Current work and future possibilities for the management of severe influenza: using immunomodulatory agents that target the host response

LM Alleva, RC Gualano, IA Clark - Future Virology, 2011 - Taylor & Francis
… However, the many complexities and nuances of disease pathogenesis during severe
influenza, as well as interactions with other conditions, remain a challenge to our deep …

Antiviral combinations for severe influenza

J Dunning, JK Baillie, B Cao… - The Lancet infectious …, 2014 - thelancet.com
… An obvious strategy to optimise antiviral therapy is to combine drugs with different modes of
… therapy and of combined antiviral-immunomodulator therapy for influenza. Early-stage data …