Favorable venous outflow profiles correlate with favorable tissue-level collaterals and clinical outcome

TD Faizy, R Kabiri, S Christensen, M Mlynash… - Stroke, 2021 - Am Heart Assoc
… Patients with acute ischemic stroke due to large vessel occlusion and favorable tissue-level
collaterals (TLCs) likely have robust cortical venous outflow (VO). We hypothesized that …

Distinct intra‐arterial clot localization affects tissuelevel collaterals and venous outflow profiles

TD Faizy, R Kabiri, S Christensen… - European Journal of …, 2021 - Wiley Online Library
… We determined the association between vessel occlusion locations, tissue-level collaterals
(TLC), and venous outflow (VO) profiles and their impact on good functional outcomes. …

The impact of flow-induced forces on the morphogenesis of the outflow tract

SV Biechler, L Junor, AN Evans, JF Eberth… - Frontiers in …, 2014 - frontiersin.org
… system of outflow tract development to test the response of embryonic OFT tissues to fluid …
Since local flow profiles influence explant morphology we characterized the flow throughout …

Molecular taxonomy of human ocular outflow tissues defined by single-cell transcriptomics

G Patel, W Fury, H Yang… - Proceedings of the …, 2020 - National Acad Sciences
… The coordinated effort of multiple cells with differing responsibilities ensures healthy outflow
… of human conventional outflow tissues. We obtained expression profiles of 17,757 genes …

[HTML][HTML] Normal and glaucomatous outflow regulation

TS Acott, JA Vranka, KE Keller, VK Raghunathan… - Progress in retinal and …, 2021 - Elsevier
… that it does not obstruct the outflow channels deeper in the tissue. While these corneoscleral
… the region that exhibit different characteristic expression profiles. This is an area of active …

Multi-scale analysis of segmental outflow patterns in human trabecular meshwork with changing intraocular pressure

JYH Chang, SJ Folz, SN Laryea… - Journal of ocular …, 2014 - liebertpub.com
… co-localization analysis between the intensity profile of the 2 tracers within each ROI (Fig.
5E)… role of collector channels in segmental outflow, 9 we isolated tissue wedges from regions of …

[HTML][HTML] Aqueous outflow regulation: Optical coherence tomography implicates pressure-dependent tissue motion

C Xin, RK Wang, S Song, T Shen, J Wen… - Experimental eye …, 2017 - Elsevier
… A passive filter at a single location in the juxtacanalicular space may solely regulate aqueous
outflow. If so, there is no need for embarking on the studies of tissue motion described in …

The aqueous outflow system as a mechanical pump: evidence from examination of tissue and aqueous movement in human and non-human primates

MA Johnstone - Journal of glaucoma, 2004 - journals.lww.com
… excursions 8 and are thus capable of driving an aqueous outflow pump. … of the outflow
tissues, the composition of the tissues, laboratory evidence of the effects of tissue loading (in this …

Intravenous tPA (tissue-type plasminogen activator) correlates with favorable venous outflow profiles in acute ischemic stroke

TD Faizy, M Mlynash, MP Marks, S Christensen… - Stroke, 2022 - Am Heart Assoc
… tPA impacts venous outflow (VO) is unknown. We investigated whether tPA improves VO
profiles on baseline computed tomography (CT) angiography (CTA) images before EVT. …

Outflow physiology of the mouse eye: pressure dependence and washout

Y Lei, DR Overby… - … & visual science, 2011 - iovs.arvojournals.org
… canal morphology and in their protein expression profile, 9 the absence of washout as shown
… the physiology of the inner wall of Schlemm's canal and the conventional outflow tissues. …