… be a promising therapeutic target in cancer immunotherapy. This review focuses on the role
of fatty acid metabolism and its interaction with the TME of ovarian cancer. The therapeutic …

Epithelial ovarian cancer (EOC) affects 43,000 women worldwide every year … ovarian cancer,
but its effectiveness remains to be demonstrated in tumors with a BRCAness (breast cancer…

… cases and 152,000 deaths each year, ovarian cancer (OC) is the seventh most prevalent
cancer and the second leading cause of death from gynecologic cancer (1). Despite advances …

Ovarian epithelial cancer (OEC) is the most lethal gynecologic malignancy. Despite current
chemotherapeutic and surgical options, this high lethality can be attributed to multiple factors, …

… ovarian cancer stem cells. This review will focus specifically on the markers used to define
… ovarian cancer stem cells, the prognostic implications of the expression of these cancer stem …

… be an option for therapy if recurrence occurs. For this purpose, we analyzed tumor genetic
alterations with potential therapeutic implications for targeted therapies and immunotherapy. …

… Further molecular therapeutic approaches, such as the modulation of apoptosis of other
genes, have been described for ovarian cancer therapy; however, their significance must still be …

… As 60%–80% of all advanced ovarian cancers are high-grade … ovarian cancer patients
than are currently considered for PARP inhibitor trials, may benefit from such targeted therapy…

… in ovarian cancer is not known. Here, we show that mTORC1 and mTORC2 were constitutively
active in ovarian cancer cell … in profound inhibition of ovarian cancer cell proliferation. The …

… Approximately 90% of malignant ovarian tumors arise from the superficial epithelium
which, although similar to the peritoneal mesothelium, will proceed to malignant …